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Recent Citations

An electron transfer path connects subunits of a mycobacterial respiratory supercomplex. Gong H, Li J et al. Science. 2018 Nov 30;362(6418). pii: eaat8923.

Folding pathway of an Ig domain is conserved on and off the ribosome. Tian P, Steward A et al. Proc Natl Acad Sci USA. 2018 Nov 27;115(48):E11284-E11293.

Tracing whale myoglobin evolution by resurrecting ancient proteins. Isogai Y, Imamura H et al. Sci Rep. 2018 Nov 15;8(1):16883.

Conformational transitions of the serotonin 5-HT3 receptor. Polovinkin L, Hassaine G et al. Nature. 2018 Nov 8;563(7730):275-279.

Germline VRC01 antibody recognition of a modified clade C HIV-1 envelope trimer and a glycosylated HIV-1 gp120 core. Borst AJ, Weidle CE et al. eLife. 2018 Nov 7;7. pii: e37688.

(Previously featured citations...)

Chimera Search

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News

November 17, 2018

Chimera production release 1.13.1 is now available; see the release notes for what's new. The Mac version requires OS 10.10 or later.

October 22, 2018

Mac users: the 1.13.1 release candidate and recent daily builds contain a fix for Mojave (OS 10.14). These versions require OS 10.10 or later.

September 21, 2018

Mac users are advised to hold off upgrading to Mojave until we find a fix for Chimera buttons not being shown until the windows containing them are resized.

(Previous news...)

Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), supported in part by the National Institutes of Health (P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

Blast Protein

The Blast Protein tool performs a blast or psiblast search of pdb or nr for sequences similar to a query, using a Web service hosted by the UCSF RBVI. The query can be:

  • a chain from a structure open in Chimera
  • a sequence pasted as plain text
  • a sequence from an alignment in Multalign Viewer
The output is a list of hits, from which all or a user-chosen subset can be retrieved:
  • as a pseudo-multiple sequence alignment (a consolidation of the pairwise alignments of individual hits to the query), automatically shown in Multalign Viewer
  • as structures (for hits from pdb), automatically superimposed according to the pseudo-multiple alignment

(More features...)

Gallery Sample

Peroxiredoxin Wreath

Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.

See also the RBVI holiday card gallery.

(More samples...)


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