Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data. Orbán-Németh Z, Beveridge R et al. Nat Protoc. 2018 Mar;13(3):478-494.
The cryo-electron microscopy structure of huntingtin. Guo Q, Bin Huang et al. Nature. 2018 Mar 1;555(7694):117-120.
A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle. Goode B, Mondal G et al. Nat Commun. 2018 Feb 23;9(1):810.
Electron cryo-microscopy structure of Ebola virus nucleoprotein reveals a mechanism for nucleocapsid-like assembly. Su Z, Wu C et al. Cell. 2018 Feb 22;172(5):966-978.e12.
A structural model of a p450-ferredoxin complex from orientation-selective double electron-electron resonance spectroscopy. Bowen AM, Johnson EOD et al. J Am Chem Soc. 2018 Feb 21;140(7):2514-2527.(Previously featured citations...)
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For a nice 3D-printing protocol that uses Chimera, see 3D Printing of Biomolecular Models for Research and Pedagogy by Da Veiga Beltrame, Tyrwhitt-Drake, et al. today in JoVE!(Previous news...)
UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), funded by the National Institutes of Health (NIGMS P41-GM103311).
UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.
Values in a plane of volume data can be shown as heights normal to the plane (a topographic map). When a single plane is displayed with Volume Viewer, the command topography will plot the values as heights in a surface.(More features...)
Thermosomes are hollow balls inside which proteins are folded. They are found in the cytosol of eukaryotes and in archaea. Eukaryotic thermosomes have 8 different protein subunits, while archaeal ones are composed of one, two or three different proteins. The one shown from Thermoplasma acidophilum has two distinct proteins colored blue and yellow, each present in 8 copies. The two proteins have 60% sequence identity and are very similar in structure. One monomer is shown as a ribbon. Actin and tubulin are folded by eukaryotic thermosomes.
Protein Data Bank model 1a6d.(More samples...)