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Recent Citations

A cyclic oligonucleotide signaling pathway in type III CRISPR-Cas systems. Kazlauskiene M, Kostiuk G et al. Science. 2017 Aug 11;357(6351):605-609.

Crystal structure and functional analysis of Leishmania major pseudoperoxidase. Chreifi G, Dejam D, Poulos TL. J Biol Inorg Chem. 2017 Aug;22(6):919-927.

RosettaES: a sampling strategy enabling automated interpretation of difficult cryo-EM maps. Frenz B, Walls AC et al. Nat Methods. 2017 Aug;14(8):797-800.

ChromEMT: Visualizing 3D chromatin structure and compaction in interphase and mitotic cells. Ou HD, Phan S et al. Science. 2017 Jul 28;357(6349):eaag0025.

Capturing protein communities by structural proteomics in a thermophilic eukaryote. Kastritis PL, O'Reilly FJ et al. Mol Syst Biol. 2017 Jul 25;13(7):936.

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Chimera Search

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March 13, 2017

For a nice 3D-printing protocol that uses Chimera, see 3D Printing of Biomolecular Models for Research and Pedagogy by Da Veiga Beltrame, Tyrwhitt-Drake, et al. today in JoVE!

December 2, 2016

Chimera production release 1.11.2 is now available. This version has been updated to work with changes in NCBI Blast and to avoid crashes on Mac Sierra (see the release notes for details).

September 24, 2016

Production release candidate (version 1.11.2) is available, superseding 1.11.1. The new version has been updated to work with changes in NCBI Blast (see release notes). Please try it and report any problems.

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Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), funded by the National Institutes of Health (NIGMS P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

coloring by bfactor

B-Factor Coloring

A structure can be colored to show values of an attribute such as atomic B-factor. The image includes a molecular surface that has been clipped and capped, 2D labels, and a color key. Color Zone was used to color the planar cross-section of the surface (see image how-to).

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Gallery Sample

Peroxiredoxin Wreath

Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.

See also the RBVI holiday card gallery.

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