Structure and inhibition of EV-D68, a virus that causes respiratory illness in children. Liu Y, Sheng J et al. Science. 2015 Jan 2;347(6217):71-4.
Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains. Shen PS, Park J et al. Science. 2015 Jan 2;347(6217):75-8.
Structure of a mammalian ryanodine receptor. Zalk R, Clarke OB et al. Nature. 2015 Jan 1;517(7532):44-9.
cddApp: A Cytoscape app for accessing the NCBI Conserved Domain Database. Morris JH, Wu A et al. Bioinformatics. 2015 Jan 1;31(1):134-6.
Does topology drive fiber polymerization? Huang L, Hsiao JP et al. Biochemistry. 2014 Dec 16;53(49):7824-34.(Previously featured citations...)
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January 9, 2015
Chimera production release 1.10.1 is now available. 64-bit builds are recommended for all capable platforms, and the 1.10 series will be the last to support OS X 10.6 and 10.7. See the release notes for details.
November 5, 2014
Chimera production release 1.10 is now available. 64-bit builds are recommended for all capable platforms, and v1.10 will be the last to support OS X 10.6 and 10.7. See the release notes for what's new.
October 23, 2014
A production release candidate (v1.10) is available; please try it and report any problems. 64-bit builds are now recommended for all capable platforms, and v1.10 will be the last to support OS X 10.6 and 10.7. See the release notes for what's new.(Previous news...)
UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics, funded by the National Institutes of Health (NIGMS P41-GM103311).
The Metal Geometry tool facilitates analysis of metal-binding sites. It lists potential metal-coordinating atoms (nearby nucleophilic heteroatoms) and suggests likely coordination geometries. An idealized geometry can be depicted with solid arrows, as shown in the figure for the octahedral coordination of Mn++ by six atoms, and the coordination pseudobonds in the structure can be updated to match the chosen geometry.(More features...)
BILD format was used in Chimera to annotate the barrel structure of green fluorescent protein with its centroid, major axis (red arrow), and an enclosing cylinder (shown with green hoops). The BILD file green.bild was generated with the python program green.py using the coordinates in green.pdb. Gallery entry courtesy of Mike Ess, Yeast Resource Center, University of Washington. (More samples...)