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Recent Citations
PyChimera: use UCSF Chimera modules in any Python 2.7 project. Rodríguez-Guerra Pedregal J, Maréchal JD. Bioinformatics. 2018 May 15;34(10):1784-1785.
Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB. Bräuning B, Bertosin E et al. Nat Commun. 2018 May 4;9(1):1806.
Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures. Lee CH, MacKinnon R. Science. 2018 May 4;360(6388):508-513.
Architecture of an HIV-1 reverse transcriptase initiation complex. Larsen KP, Mathiharan YK et al. Nature. 2018 May;557(7703):118-122.
Computational 3D genome modeling using Chrom3D. Paulsen J, Liyakat Ali TM, Collas P. Nat Protoc. 2018 May;13(5):1137-1152.
(Previously featured citations...)Chimera Search
Google™ SearchNews
October 24, 2017
Chimera production release 1.12 is now available (64-bit builds for Windows, Mac, and Linux). See the release notes for details.
September 12, 2017
A production release candidate (version 1.12) is available; please try it and report any problems. See the release notes for what's new.
March 13, 2017
For a nice 3D-printing protocol that uses Chimera, see 3D Printing of Biomolecular Models for Research and Pedagogy by Da Veiga Beltrame, Tyrwhitt-Drake, et al. today in JoVE!
(Previous news...)Upcoming Events
UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), supported in part by the National Institutes of Health (NIGMS P41-GM103311).
UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.
Feature Highlight
Gallery Sample
Side-by-side views of a potassium channel structure (Protein Data Bank entry 1bl8) showing different approaches to cavity detection. On the left are molecular surface patches corresponding to the structure's two largest pockets by MS volume in the Computed Atlas of Surface Topography of proteins (CASTp) database. On the right is a tunnel in blue identified by the MolAxis server. Simple editing converted MolAxis output into a BILD file for display in Chimera. (More samples...)