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Recent Citations

Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser. Nogly P, Weinert T et al. Science. 2018 Jul 13;361(6398). pii: eaat0094.

Structural analysis of influenza vaccine virus-like particles reveals a multicomponent organization. McCraw DM, Gallagher JR et al. Sci Rep. 2018 Jul 9;8(1):10342.

Repurposing drugs to target the malaria parasite unfolding protein response. Chen Y, Murillo-Solano C et al. Sci Rep. 2018 Jul 9;8(1):10333.

Structure of a human synaptic GABAA receptor. Zhu S, Noviello CM et al. Nature. 2018 Jul 5;559(7712):67-72.

Modeling protein complexes using restraints from crosslinking mass spectrometry. Bullock JMA, Sen N et al. Structure. 2018 Jul 3;26(7):1015-1024.e2.

(Previously featured citations...)

Chimera Search

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July 3, 2018

Chimera production release 1.13 is now available. See the release notes for what's new.

June 2, 2018

A production release candidate (version 1.13) is available; please try it and report any problems. See the release notes for what's new.

October 24, 2017

Chimera production release 1.12 is now available (64-bit builds for Windows, Mac, and Linux). See the release notes for details.

(Previous news...)

Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), supported in part by the National Institutes of Health (P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

Fly-through Animation

The fly command can animate a flight through molecular structures. Click the example image to fly along the RNA being copied by rotavirus RNA polymerase (PDB 2r7r), an enzyme that replicates the 11 segments of viral RNA. See a video showing how this animation was made.

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Gallery Sample

Sliced Potassium Channel

Potassium channel (Protein Data Bank entry 1bl8) on a dark slate blue background with potassium ions shown in firebrick. The channel is comprised of four chains. Each chain has been rainbow-colored from blue at the N-terminus to red at the C-terminus, but only the surface of the channel is shown. The surface has been sliced with a per-model clipping plane. The surface cap color is plum except with opacity set to 0.8. The shininess and brightness have been set to 128 and 8, respectively, and the lights on the scene have been moved from their default positions. The subdivision quality (related to the smoothness of the spherical ions) is 5.0, and the molecular surface was computed with probe radius and vertex density set to 1.0 and 6.0, respectively. (More samples...)