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Recent Citations
The bacteriophage T7 virion undergoes extensive structural remodeling during infection. Hu B, Margolin W et al. Science. 2013 Feb 1;339(6119):576-9.
HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation. Filbin ME, Vollmar BS et al. Nat Struct Mol Biol. 2013 Feb;20(2):150-8.
A radically configurable six-state compound. Barnes JC, Fahrenbach AC et al. Science. 2013 Jan 25;339(6118):429-33.
Molecular structures of trimeric HIV-1 Env in complex with small antibody derivatives. Meyerson JR, Tran EE et al. Proc Natl Acad Sci USA. 2013 Jan 8;110(2):513-8.
Structural characterization of a eukaryotic chaperone — the ribosome-associated complex. Leidig C, Bange G et al. Nat Struct Mol Biol. 2013 Jan;20(1):23-8.
(Previously featured citations...)Chimera Search
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January 30, 2013
Chimera production release 1.7 is now available. See the release notes for new features since the 1.6 release series. Mac PowerPC and OS X 10.5 are no longer supported.
January 17, 2013
A production release candidate (version 1.7) is now available; please try it and report any problems. See the release notes for changes relative to the previous release. Mac PowerPC and OS X 10.5 are no longer supported.
December 17, 2012
The ViewMotions Server (from the Kantrowitz Lab, Boston College) shows protein conformational changes as a series of structures rainbow-colored from blue to red. Results include an image and a Chimera session file.
(Previous news...)Upcoming Events
UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics, funded by the National Institutes of Health (NIGMS P41-GM103311).
Feature Highlight
Chimera's Volume Viewer displays three-dimensional electron and light microscope data, X-ray density maps, electrostatic potential and other volumetric data. Contour surfaces, meshes and volumetric display styles are provided and thresholds can be changed interactively. Maps can be colored, sliced, segmented, and modifications can be saved. Markers can be placed and structures can be traced. The accompanying image shows a density map of Kelp fly virus from electron microscopy colored radially and with an octant cut out.
(More features...)Gallery Sample
Potassium channel (Protein Data Bank entry 1bl8) on a dark slate blue background with potassium ions shown in firebrick. The channel is comprised of four chains. Each chain has been rainbow-colored from blue at the N-terminus to red at the C-terminus, but only the surface of the channel is shown. The surface has been sliced with a per-model clipping plane. The surface cap color is plum except with opacity set to 0.8. The shininess and brightness have been set to 128 and 8, respectively, and the lights on the scene have been moved from their default positions. The subdivision quality (related to the smoothness of the spherical ions) is 5.0, and the molecular surface was computed with probe radius and vertex density set to 1.0 and 6.0, respectively. (More samples...)