about projects people publications resources resources visit us visit us search search

Quick Links

Recent Citations

Observation of a promethium complex in solution. Driscoll DM, White FD et al. Nature. 2024 May 23;629(8013):819-823.

Stepwise activation of a metabotropic glutamate receptor. Krishna Kumar K, Wang H et al. Nature. 2024 May 23;629(8013):951–956.

Structural basis of lipid head group entry to the Kennedy pathway by FLVCR1. Son Y, Kenny TC et al. Nature. 2024 May 16;629(8012):710–716.

Structural and molecular basis of choline uptake into the brain by FLVCR2. Cater RJ, Mukherjee D et al. Nature. 2024 May 16;629(8012):704–709.

Promiscuous G-protein activation by the calcium-sensing receptor. Zuo H, Park J et al. Nature. 2024 May 9;629(8011):481–488.

Previously featured citations...

Chimera Search

Google™ Search

News

October 30-31, 2023

Planned downtime: The Chimera and ChimeraX websites and associated web services will be unavailable Oct 30 8am PDT – Oct 31 11:59pm PDT.

April 19, 2023

Chimera production release 1.17.1 is now available, fixing an issue with 1.17 for Windows and Linux. See the release notes for details.

April 13, 2023

Chimera production release 1.17 is now available. Updating is required to keep using the tools that run Blast Protein, Modeller, and multiple sequence alignment with Clustal Omega or MUSCLE, as these will soon stop working in older versions. See the release notes for details.

Previous news...

Upcoming Events

Please note that UCSF Chimera is legacy software that is no longer being developed or supported. Users are strongly encouraged to try UCSF ChimeraX, which is under active development.

UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.

We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features in addition to nearly all the capabilities of Chimera (details...).

Chimera is no longer under active development. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.

Feature Highlight

EM map morph

Morphing Density Maps

Related density maps can be compared by morphing from one to the other. Several intermediate maps are generated by interpolating between the starting and ending maps. The morph can be viewed interactively and recorded as a movie. The contour level can be adjusted automatically to keep the enclosed volume constant throughout the morph, and other aspects of map display can be adjusted with Volume Viewer.

(More features...)

Gallery Sample

G Protein Interface Surface

Heterotrimeric G protein (Protein Data Bank entry 1gg2) with the alpha subunit shown in green, the beta subunit in light blue, and the gamma subunit in brown. The Intersurf tool was used to show the interface between the alpha and beta subunits. The interface surface is colored to show the distance between atoms across the interface (red for closer together, blue for farther apart). (More samples...)


About RBVI | Projects | People | Publications | Resources | Visit Us

Copyright 2018 Regents of the University of California. All rights reserved.