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Citations (partial list)

Craspase is a CRISPR RNA-guided, RNA-activated protease. Hu C, van Beljouw SPB et al. Science. 2022 Sep 16;377(6612):1278-1285.

Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Ehara H, Kujirai T et al. Science. 2022 Sep 9;377(6611):eabp9466.

Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex. Kwon JJ, Hajian B et al. Nature. 2022 Sep 8;609(7926):408-415.

Archaic chaperone-usher pili self-secrete into superelastic zigzag springs. Pakharukova N, Malmi H et al. Nature. 2022 Sep 8;609(7926):335-340.

Structure of Tetrahymena telomerase-bound CST with polymerase α-primase. He Y, Song H et al. Nature. 2022 Aug 25;608(7924):813-818.

In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM. Huang CY, Draczkowski P et al. Nat Commun. 2022 Aug 19;13(1):4877.

Cryo-EM structures of two human B cell receptor isotypes. Ma X, Zhu Y et al. Science. 2022 Aug 19;377(6608):880-885.

Intermediates in SARS-CoV-2 spike-mediated cell entry. Marcink TC, Kicmal T et al. Sci Adv. 2022 Aug 19;8(33):eabo3153.

Architecture and self-assembly of the jumbo bacteriophage nuclear shell. Laughlin TG, Deep A et al. Nature. 2022 Aug 11;608(7922):429-435.

Implementation of occupied and virtual Edmiston-Ruedenberg orbitals using Cholesky decomposed integrals. Folkestad SD, Matveeva R et al. J Chem Theory Comput. 2022 Aug 9;18(8):4733-4744.

Integrative genome modeling platform reveals essentiality of rare contact events in 3D genome organizations. Boninsegna L, Yildirim A et al. Nat Methods. 2022 Aug;19(8):938-949.

Membrane-anchored HDCR nanowires drive hydrogen-powered CO2 fixation. Dietrich HM, Righetto RD et al. Nature. 2022 Jul 28;607(7920):823-830.

Fusion protein strategies for cryo-EM study of G protein-coupled receptors. Zhang K, Wu H et al. Nat Commun. 2022 Jul 28;13(1):4366.

Characterizing and explaining the impact of disease-associated mutations in proteins without known structures or structural homologs. Sen N, Anishchenko I et al. Brief Bioinform. 2022 Jul 18;23(4):bbac187.

A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel. Feng P, Wu X et al. Nature. 2022 Jul 14;607(7918):374-380.

2.7 Å cryo-EM structure of ex vivo RML prion fibrils. Manka SW, Zhang W et al. Nat Commun. 2022 Jul 13;13(1):4004.

Cryo-EM structure of a type IV secretion system. Macé K, Vadakkepat AK et al. Nature. 2022 Jul 7;607(7917):191-196.

Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate. McCorvie TJ, Loria PM et al. Nat Struct Mol Biol. 2022 Jul;29(7):628-638.

Structural basis of sodium-dependent bile salt uptake into the liver. Goutam K, Ielasi FS et al. Nature. 2022 Jun 30;606(7916):1015-1020.

Structure of the bile acid transporter and HBV receptor NTCP. Asami J, Kimura KT et al. Nature. 2022 Jun 30;606(7916):1021-1026.

Structural basis of GABA reuptake inhibition. Motiwala Z, Aduri NG et al. Nature. 2022 Jun 23;606(7915):820-826.

Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon. Hilal T, Killam BY et al. Science. 2022 Jun 17;376(6599):1338-1343.

Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex. Zhu X, Huang G et al. Science. 2022 Jun 10;376(6598):eabl8280.

Architecture of the cytoplasmic face of the nuclear pore. Bley CJ, Nie S et al. Science. 2022 Jun 10;376(6598):eabm9129.

Architecture of the linker-scaffold in the nuclear pore. Petrovic S, Samanta D et al. Science. 2022 Jun 10;376(6598):eabm9798.

Targeted isolation of diverse human protective broadly neutralizing antibodies against SARS-like viruses. He WT, Musharrafieh R et al. Nat Immunol. 2022 Jun;23(6):960-970.

A feature-guided, focused 3D signal permutation method for subtomogram averaging. Peters JJ, Leitz J et al. J Struct Biol. 2022 Jun;214(2):107851.

Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes. Wang C, Hesketh EL et al. Nat Commun. 2022 May 25;13(1):2921.

Posttranslational modification of microtubules by the MATCAP detyrosinase. Landskron L, Bak J et al. Science. 2022 May 20;376(6595):eabn6020.

Opening of glutamate receptor channel to subconductance levels. Yelshanskaya MV, Patel DS et al. Nature. 2022 May 5;605(7908):172-178.

Novel fold of rotavirus glycan-binding domain predicted by AlphaFold2 and determined by X-ray crystallography. Hu L, Salmen W et al. Commun Biol. 2022 May 5;5(1):419.

Cryo-EM structure of an active central apparatus. Han L, Rao Q et al. Nat Struct Mol Biol. 2022 May;29(5):472-482.

Cryo-EM structure of the EBV ribonucleotide reductase BORF2 and mechanism of APOBEC3B inhibition. Shaban NM, Yan R et al. Sci Adv. 2022 Apr 29;8(17):eabm2827.

Structural basis of tethered agonism of the adhesion GPCRs ADGRD1 and ADGRF1. Qu X, Qiu N et al. Nature. 2022 Apr 28;604(7907):779–785.

Three-dimensional structure determination of protein complexes using matrix-landing mass spectrometry. Westphall MS, Lee KW et al. Nat Commun. 2022 Apr 27;13(1):2276.

Computational design of mechanically coupled axle-rotor protein assemblies. Courbet A, Hansen J et al. Science. 2022 Apr 22;376(6591):383-390.

Molecular basis of receptor binding and antibody neutralization of Omicron. Hong Q, Han W et al. Nature. 2022 Apr 21;604(7906):546–552.

Activation of STING by targeting a pocket in the transmembrane domain. Lu D, Shang G et al. Nature. 2022 Apr 21;604(7906):557–562.

Structure deformation and curvature sensing of PIEZO1 in lipid membranes. Yang X, Lin C et al. Nature. 2022 Apr 14;604(7905):377–383.

Structure, substrate recognition and initiation of hyaluronan synthase. Maloney FP, Kuklewicz J et al. Nature. 2022 Apr 7;604(7904):195–201.

Identification of functional substates of KRas during GTP hydrolysis with enhanced sampling simulations. Zeng J, Chen J et al. Phys Chem Chem Phys. 2022 Mar 30;24(13):7653-7665.

SINAPs: A software tool for analysis and visualization of interaction networks of molecular dynamics simulations. Bedart C, Renault N et al. J Chem Inf Model. 2022 Mar 28;62(6):1425-1436.

A structural basis for amylin receptor phenotype. Cao J, Belousoff MJ et al. Science. 2022 Mar 25;375(6587):eabm9609.

Activation mechanism of the class D fungal GPCR dimer Ste2. Velazhahan V, Ma N et al. Nature. 2022 Mar 24;603(7902):743-748.

Concise syntheses of GB22, GB13, and himgaline by cross-coupling and complete reduction. Landwehr EM, Baker MA et al. Science. 2022 Mar 18;375(6586):1270-1274.

Bacterial ribosome collision sensing by a MutS DNA repair ATPase paralogue. Cerullo F, Filbeck S et al. Nature. 2022 Mar 17;603(7901):509–514.

Discovery of a Ni2+-dependent guanidine hydrolase in bacteria. Funck D, Sinn M et al. Nature. 2022 Mar 17;603(7901):515–521.

Cryo-EM structure and electrophysiological characterization of ALMT from Glycine max reveal a previously uncharacterized class of anion channels. Qin L, Tang LH et al. Sci Adv. 2022 Mar 4;8(9):eabm3238.

Structure and receptor recognition by the Lassa virus spike complex. Katz M, Weinstein J et al. Nature. 2022 Mar 3;603(7899):174-179.

Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase. Sverzhinsky A, Tomkinson AE, Pascal JM. Structure. 2022 Mar 3;30(3):371-385.e5.

Mechanism of signal sequence handover from NAC to SRP on ribosomes during ER-protein targeting. Jomaa A, Gamerdinger M et al. Science. 2022 Feb 25;375(6583):839-844.

Visualizing protein breathing motions associated with aromatic ring flipping. Mariño Pérez L, Ielasi FS et al. Nature. 2022 Feb 24;602(7898):695-700.

SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein-ACE2 complex. Mannar D, Saville JW et al. Science. 2022 Feb 18;375(6582):760-764.

Mechanisms of inhibition and activation of extrasynaptic αβ GABA(A) receptors. Kasaragod VB, Mortensen M et al. Nature. 2022 Feb 17;602(7897):529-533.

Broadly neutralizing antibodies target a haemagglutinin anchor epitope. Guthmiller JJ, Han J et al. Nature. 2022 Feb 10;602(7896):314–320.

Acid-stable capsid structure of Helicobacter pylori bacteriophage KHP30 by single-particle cryoelectron microscopy. Kamiya R, Uchiyama J et al. Structure. 2022 Feb 3;30(2):300-312.e3.

The amyloid concentric β-barrel hypothesis: Models of synuclein oligomers, annular protofibrils, lipoproteins, and transmembrane channels. Durell SR, Guy HR. Proteins. 2022 Feb;90(2):512-542.

Structural insights into inhibitor regulation of the DNA repair protein DNA-PKcs. Liang S, Thomas SE et al. Nature. 2022 Jan 27;601(7894):643–648.

Structural insights into the BRAF monomer-to-dimer transition mediated by RAS binding. Martinez Fiesco JA, Durrant DE et al. Nat Commun. 2022 Jan 25;13(1):486.

From structure to sequence: Antibody discovery using cryoEM. Antanasijevic A, Bowman CA et al. Sci Adv. 2022 Jan 21;8(3):eabk2039.

Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism. Wang RY, Noddings CM et al. Nature. 2022 Jan 20;601(7893):460–464.

Comprehensive structure and functional adaptations of the yeast nuclear pore complex. Akey CW, Singh D et al. Cell. 2022 Jan 20;185(2):361-378.e25.

Structure and mechanism of the SGLT family of glucose transporters. Han L, Qu Q et al. Nature. 2022 Jan 13;601(7892):274–279.

Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex. Patil DN, Singh S et al. Science. 2022 Jan 7;375(6576):86-91.

Leveraging crosslinking mass spectrometry in structural and cell biology. Graziadei A, Rappsilber J. Structure. 2022 Jan 6;30(1):37-54.

Integrative structural modeling of macromolecular complexes using Assembline. Rantos V, Karius K, Kosinski J. Nat Protoc. 2022 Jan;17(1):152-176.

Structure and plasticity of indoleamine 2,3-dioxygenase 1 (IDO1). Röhrig UF, Michielin O, Zoete V. J Med Chem. 2021 Dec 23;64(24):17690-17705.

Structure and RNA template requirements of Arabidopsis RNA-DEPENDENT RNA POLYMERASE 2. Fukudome A, Singh J et al. Proc Natl Acad Sci USA. 2021 Dec 21;118(51):e2115899118.

The conformational cycle of prestin underlies outer-hair cell electromotility. Bavi N, Clark MD et al. Nature. 2021 Dec 16;600(7889):553–558.

Computed structures of core eukaryotic protein complexes. Humphreys IR, Pei J et al. Science. 2021 Dec 10;374(6573):eabm4805.

Structures of the HER2-HER3-NRG1β complex reveal a dynamic dimer interface. Diwanji D, Trenker R et al. Nature. 2021 Dec 9;600(7888):339–343.

Structure, function and pharmacology of human itch receptor complexes. Yang F, Guo L et al. Nature. 2021 Dec 2;600(7887):164–169.

The human microbiome encodes resistance to the antidiabetic drug acarbose. Balaich J, Estrella M et al. Nature. 2021 Dec 2;600(7887):110-115.

Molecular structure of an open human KATP channel. Zhao C, MacKinnon R. Proc Natl Acad Sci USA. 2021 Nov 30;118(48):e2112267118.

Human RIPK3 maintains MLKL in an inactive conformation prior to cell death by necroptosis. Meng Y, Davies KA et al. Nat Commun. 2021 Nov 22;12(1):6783.

A viral RNA hijacks host machinery using dynamic conformational changes of a tRNA-like structure. Bonilla SL, Sherlock ME et al. Science. 2021 Nov 19;374(6570):955-960.

AKIRIN2 controls the nuclear import of proteasomes in vertebrates. de Almeida M, Hinterndorfer M et al. Nature. 2021 Nov 18;599(7885):491-496.

Dispatched uses Na+ flux to power release of lipid-modified Hedgehog. Wang Q, Asarnow DE et al. Nature. 2021 Nov 11;599(7884):320-324.

Kainate receptor modulation by NETO2. He L, Sun J et al. Nature. 2021 Nov 11;599(7884):325-329.

Mapping the catalytic conformations of an assembly-line polyketide synthase module. Cogan DP, Zhang K et al. Science. 2021 Nov 5;374(6568):729-734.

Bluetongue virus capsid protein VP5 perforates membranes at low endosomal pH during viral entry. Xia X, Wu W et al. Nat Microbiol. 2021 Nov;6(11):1424-1432.

The cellular environment shapes the nuclear pore complex architecture. Schuller AP, Wojtynek M et al. Nature. 2021 Oct 28;598(7882):667–671.

Pan-ebolavirus protective therapy by two multifunctional human antibodies. Gilchuk P, Murin CD et al. Cell. 2021 Oct 28;184(22):5593-5607.e18.

Mechanism for Cas4-assisted directional spacer acquisition in CRISPR-Cas. Hu C, Almendros C et al. Nature. 2021 Oct 21;598(7881):515-520.

Molecular ruler mechanism and interfacial catalysis of the integral membrane acyltransferase PatA. Anso I, Basso LGM et al. Sci Adv. 2021 Oct 15;7(42):eabj4565.

Structural basis of human transcription-DNA repair coupling. Kokic G, Wagner FR et al. Nature. 2021 Oct 14;598(7880):368-372.

The stress-sensing domain of activated IRE1α forms helical filaments in narrow ER membrane tubes. Tran NH, Carter SD et al. Science. 2021 Oct 1;374(6563):52-57.

A practical guide to large-scale docking. Bender BJ, Gahbauer S et al. Nat Protoc. 2021 Oct;16(10):4799-4832.

The tertiary structure of the human Xkr8-Basigin complex that scrambles phospholipids at plasma membranes. Sakuragi T, Kanai R et al. Nat Struct Mol Biol. 2021 Oct;28(10):825-834.

Gastric proton pump with two occluded K+ engineered with sodium pump-mimetic mutations. Abe K, Yamamoto K et al. Nat Commun. 2021 Sep 29;12(1):5709.

Structural insights into the inhibition of undecaprenyl pyrophosphate synthase from Gram-positive bacteria. Workman SD, Day J et al. J Med Chem. 2021 Sep 23;64(18):13540-13550.

Cryo-EM structure of the Rhodospirillum rubrum RC-LH1 complex at 2.5 Å. Qian P, Croll TI et al. Biochem J. 2021 Sep 17;478(17):3253-3263.

Structural basis of RNA polymerase inhibition by viral and host factors. Pilotto S, Fouqueau T et al. Nat Commun. 2021 Sep 17;12(1):5523.

Structure of Geobacter pili reveals secretory rather than nanowire behaviour. Gu Y, Srikanth V et al. Nature. 2021 Sep 16;597(7876):430-434.

In situ cryo-electron tomography reveals gradient organization of ribosome biogenesis in intact nucleoli. Erdmann PS, Hou Z et al. Nat Commun. 2021 Sep 10;12(1):5364.

Broad betacoronavirus neutralization by a stem helix-specific human antibody. Pinto D, Sauer MM et al. Science. 2021 Sep 3;373(6559):1109-1116.

Evolving cryo-EM structural approaches for GPCR drug discovery. Zhang X, Johnson RM et al. Structure. 2021 Sep 2;29(9):963-974.e6.

Molecular mechanism of prestin electromotive signal amplification. Ge J, Elferich J et al. Cell. 2021 Sep 2;184(18):4669-4679.e13.

Practical considerations for using K3 cameras in CDS mode for high-resolution and high-throughput single particle cryo-EM. Sun M, Azumaya CM et al. J Struct Biol. 2021 Sep;213(3):107745.

Structural basis of RNA processing by human mitochondrial RNase P. Bhatta A, Dienemann C et al. Nat Struct Mol Biol. 2021 Sep;28(9):713-723.


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