Structural basis of pan-Ebolavirus neutralization by an antibody targeting the glycoprotein fusion loop. Murin CD, Bruhn JF et al. Cell Rep. 2018 Sep 4;24(10):2723-2732.e4.

Electron-microscopy-based epitope mapping defines specificities of polyclonal antibodies elicited during HIV-1 BG505 envelope trimer immunization. Bianchi M, Turner HL et al. Immunity. 2018 Aug 21;49(2):288-300.e8.

Structure-based design of a monosaccharide ligand targeting galectin-8. Bohari MH, Yu X et al. ChemMedChem. 2018 Aug 20;13(16):1664-1672.

Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs. Matthies D, Bae C et al. eLife. 2018 Aug 15;7. pii: e37558.

Structure and analysis of R1 and R2 pyocin receptor-binding fibers. Buth SA, Shneider MM et al. Viruses. 2018 Aug 14;10(8). pii: E427.

Cryo-EM of the dynamin polymer assembled on lipid membrane. Kong L, Sochacki KA et al. Nature. 2018 Aug 9;560(7717):258-262.

Structural basis of cell wall anchoring by SLH domains in Paenibacillus alvei. Blackler RJ, López-Guzmán A et al. Nat Commun. 2018 Aug 7;9(1):3120.

Insights into centriole geometry revealed by cryotomography of doublet and triplet centrioles. Greenan GA, Keszthelyi B et al. eLife. 2018 Aug 6;7. pii: e36851.

Structure of mouse protocadherin 15 of the stereocilia tip link in complex with LHFPL5. Ge J, Elferich J et al. eLife. 2018 Aug 2;7. pii: e38770.

Cryo-EM structure of the αvβ8 integrin reveals a mechanism for stabilizing integrin extension. Cormier A, Campbell MG et al. Nat Struct Mol Biol. 2018 Aug;25(8):698-704.

A new HIV-1 Rev structure optimizes interaction with target RNA (RRE) for nuclear export. Watts NR, Eren E et al. J Struct Biol. 2018 Aug;203(2):102-108.

Expanded coverage of the 26S proteasome conformational landscape reveals mechanisms of peptidase gating. Eisele MR, Reed RG et al. Cell Rep. 2018 Jul 31;24(5):1301-1315.e5.

Cryo-EM structures of fungal and metazoan mitochondrial calcium uniporters. Baradaran R, Wang C et al. Nature. 2018 Jul 26;559(7715):580-584.

HIV-1 Nefs are cargo-sensitive AP-1 trimerization switches in tetherin downregulation. Morris KL, Buffalo CZ et al. Cell. 2018 Jul 26;174(3):659-671.e14.

Prespliceosome structure provides insights into spliceosome assembly and regulation. Plaschka C, Lin PC et al. Nature. 2018 Jul 19;559(7714):419-422.

Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser. Nogly P, Weinert T et al. Science. 2018 Jul 13;361(6398). pii: eaat0094.

Structural analysis of influenza vaccine virus-like particles reveals a multicomponent organization. McCraw DM, Gallagher JR et al. Sci Rep. 2018 Jul 9;8(1):10342.

Repurposing drugs to target the malaria parasite unfolding protein response. Chen Y, Murillo-Solano C et al. Sci Rep. 2018 Jul 9;8(1):10333.

Glycan recognition in globally dominant human rotaviruses. Hu L, Sankaran B et al. Nat Commun. 2018 Jul 6;9(1):2631.

Structure of a human synaptic GABA_A receptor. Zhu S, Noviello CM et al. Nature. 2018 Jul 5;559(7712):67-72.

Modeling protein complexes using restraints from crosslinking mass spectrometry. Bullock JMA, Sen N et al. Structure. 2018 Jul 3;26(7):1015-1024.e2.

Inhibitors of the HIV-1 capsid, a target of opportunity. Carnes SK, Sheehan JH, Aiken C. Curr Opin HIV AIDS. 2018 Jul;13(4):359-365.

Structure of the adenosine-bound human adenosine A1 receptor-Gi complex. Draper-Joyce CJ, Khoshouei M et al. Nature. 2018 Jun 28;558(7711):559-563.

Self-assembly of highly symmetrical, ultrasmall inorganic cages directed by surfactant micelles. Ma K, Gong Y et al. Nature. 2018 Jun 28;558(7711):577-580.

Structural basis of mitochondrial receptor binding and constriction by DRP1. Kalia R, Wang RY et al. Nature. 2018 Jun 21;558(7710):401-405.

Structural basis for regulation of human acetyl-CoA carboxylase. Hunkeler M, Hagmann A et al. Nature. 2018 Jun 21;558(7710):470-474.

Co-evolution of HIV envelope and apex-targeting neutralizing antibody lineage provides benchmarks for vaccine design. Rantalainen K, Berndsen ZT et al. Cell Rep. 2018 Jun 12;23(11):3249-3261.

In vivo production of RNA nanostructures via programmed folding of single-stranded RNAs. Li M, Zheng M et al. Nat Commun. 2018 Jun 6;9(1):2196.

Structures of jacalin-related lectin PPL3 regulating pearl shell biomineralization. Nakae S, Shionyu M et al. Proteins. 2018 Jun;86(6):644-653.

Routine single particle CryoEM sample and grid characterization by tomography. Noble AJ, Dandey VP et al. eLife. 2018 May 29;7. pii: e34257

Structure of telomerase with telomeric DNA. Jiang J, Wang Y et al. Cell. 2018 May 17;173(5):1179-1190.e13.

PyChimera: use UCSF Chimera modules in any Python 2.7 project. Rodríguez-Guerra Pedregal J, Maréchal JD. Bioinformatics. 2018 May 15;34(10):1784-1785.

Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S. Trastoy B, Klontz E et al. Nat Commun. 2018 May 14;9(1):1874.

Structure and mechanism of the two-component α-helical pore-forming toxin YaxAB. Bräuning B, Bertosin E et al. Nat Commun. 2018 May 4;9(1):1806.

Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures. Lee CH, MacKinnon R. Science. 2018 May 4;360(6388):508-513.

Architecture of an HIV-1 reverse transcriptase initiation complex. Larsen KP, Mathiharan YK et al. Nature. 2018 May;557(7703):118-122.

Computational 3D genome modeling using Chrom3D. Paulsen J, Liyakat Ali TM, Collas P. Nat Protoc. 2018 May;13(5):1137-1152.

From structure to function - a family portrait of plant subtilases. Schaller A, Stintzi A et al. New Phytol. 2018 May;218(3):901-915.

Structural basis for energy transduction by respiratory alternative complex III. Sousa JS, Calisto F et al. Nat Commun. 2018 Apr 30;9(1):1728.

Asymmetric distribution and spatial switching of dynein activity generates ciliary motility. Lin J, Nicastro D. Science. 2018 Apr 27;360(6387). pii: eaar1968.

Structure of a prehandover mammalian ribosomal SRP·SRP receptor targeting complex. Kobayashi K, Jomaa A et al. Science. 2018 Apr 20;360(6386):323-327.

Cryo-EM structure of the Blastochloris viridis LH1-RC complex at 2.9 Å. Qian P, Siebert CA et al. Nature. 2018 Apr 12;556(7700):203-208.

Structure of the herpes simplex virus 1 capsid with associated tegument protein complexes. Dai X, Zhou ZH. Science. 2018 Apr 6;360(6384). pii: eaao7298.

Structural rearrangements of the histone octamer translocate DNA. Bilokapic S, Strauss M, Halic M. Nat Commun. 2018 Apr 6;9(1):1330.

Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Scapin G, Dandey VP et al. Nature. 2018 Apr 5;556(7699):122-125.

Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule. Tsai JC, Miller-Vedam LE et al. Science. 2018 Mar 30;359(6383).

Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B. Zyryanova AF, Weis F et al. Science. 2018 Mar 30;359(6383):1533-1536.

EF-Tu and EF-G are activated by allosteric effects. Mondal D, Warshel A. Proc Natl Acad Sci USA. 2018 Mar 27;115(13):3386-3391.

Ligand binding site structure influences the evolution of protein complex function and topology. Abrusán G, Marsh JA. Cell Rep. 2018 Mar 20;22(12):3265-3276.

Lipids shape the electron acceptor-binding site of the peripheral membrane protein dihydroorotate dehydrogenase. Costeira-Paulo J, Gault J et al. Cell Chem Biol. 2018 Mar 15;25(3):309-317.e4.

The 3.5-Å cryoEM structure of nanodisc-reconstituted yeast vacuolar ATPase Vo proton channel. Roh SH, Stam NJ et al. Mol Cell. 2018 Mar 15;69(6):993-1004.e3.

Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility. Grotjahn DA, Chowdhury S et al. Nat Struct Mol Biol. 2018 Mar;25(3):203-207.

The cryo-electron microscopy structure of huntingtin. Guo Q, Bin Huang et al. Nature. 2018 Mar 1;555(7694):117-120.

Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data. Orbán-Németh Z, Beveridge R et al. Nat Protoc. 2018 Mar;13(3):478-494.

A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle. Goode B, Mondal G et al. Nat Commun. 2018 Feb 23;9(1):810.

Electron cryo-microscopy structure of Ebola virus nucleoprotein reveals a mechanism for nucleocapsid-like assembly. Su Z, Wu C et al. Cell. 2018 Feb 22;172(5):966-978.e12.

A structural model of a p450-ferredoxin complex from orientation-selective double electron-electron resonance spectroscopy. Bowen AM, Johnson EOD et al. J Am Chem Soc. 2018 Feb 21;140(7):2514-2527.

3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound. Brignole EJ, Tsai KL et al. eLife. 2018 Feb 20;7. pii: e31502.

A global view of structure-function relationships in the tautomerase superfamily. Davidson R, Baas BJ et al. J Biol Chem. 2018 Feb 16;293(7):2342-2357.

Cryo-EM reconstruction of Type VI secretion system baseplate and sheath distal end. Nazarov S, Schneider JP et al. EMBO J. 2018 Feb 15;37(4). pii: e97103.

Cryo-EM shows how dynactin recruits two dyneins for faster movement. Urnavicius L, Lau CK et al. Nature. 2018 Feb 7;554(7691):202-206.

Structural insights into the mechanisms of CNBD channel function. James ZM, Zagotta WN. J Gen Physiol. 2018 Feb 5;150(2):225-244.

Structure of the yeast oligosaccharyltransferase complex gives insight into eukaryotic N-glycosylation. Wild R, Kowal J et al. Science. 2018 Feb 2;359(6375):545-550.

Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes. Poepsel S, Kasinath V, Nogales E. Nat Struct Mol Biol. 2018 Feb;25(2):154-162.

Structure and mutagenesis reveal essential capsid protein interactions for KSHV replication. Dai X, Gong D et al. Nature. 2018 Jan 25;553(7689):521-525.

A systematic analysis of nucleosome core particle and nucleosome-nucleosome stacking structure. Korolev N, Lyubartsev AP, Nordenskiöld L. Sci Rep. 2018 Jan 24;8(1):1543.

A self-assembled nanoscale robotic arm controlled by electric fields. Kopperger E, List J et al. Science. 2018 Jan 19;359(6373):296-301.

Multiplexed gene synthesis in emulsions for exploring protein functional landscapes. Plesa C, Sidore AM et al. Science. 2018 Jan 19;359(6373):343-347.

Dicer uses distinct modules for recognizing dsRNA termini. Sinha NK, Iwasa J et al. Science. 2018 Jan 19;359(6373):329-334.

Structure of the human TRPM4 ion channel in a lipid nanodisc. Autzen HE, Myasnikov AG et al. Science. 2018 Jan 12;359(6372). pii: eaar4510.

Cryo EM structure of intact rotary H⁺-ATPase/synthase from Thermus thermophilus. Nakanishi A, Kishikawa JI et al. Nat Commun. 2018 Jan 8;9(1):89.

Site-specific disulfide crosslinked nucleosomes with enhanced stability. Frouws TD, Barth PD, Richmond TJ. J Mol Biol. 2018 Jan 5;430(1):45-57.

Development of a genetically encodable FRET system using fluorescent RNA aptamers. Jepsen MDE, Sparvath SM et al. Nat Commun. 2018 Jan 2;9(1):18.

Integrative structure modeling with the Integrative Modeling Platform. Webb B, Viswanath S et al. Protein Sci. 2018 Jan;27(1):245-258.

Cryo-EM structure of the bifunctional secretin complex of Thermus thermophilus. D'Imprima E, Salzer R et al. eLife. 2017 Dec 27;6. pii: e30483.

Proteasomes tether to two distinct sites at the nuclear pore complex. Albert S, Schaffer M et al. Proc Natl Acad Sci USA. 2017 Dec 26;114(52):13726-13731.

Structural studies of Chikungunya virus maturation. Yap ML, Klose T et al. Proc Natl Acad Sci USA. 2017 Dec 26;114(52):13703-13707.

Acquisition of functions on the outer capsid surface during evolution of double-stranded RNA fungal viruses. Mata CP, Luque D et al. PLoS Pathog. 2017 Dec 8;13(12):e1006755.

Structure of the yeast spliceosomal postcatalytic P complex. Liu S, Li X et al. Science. 2017 Dec 8;358(6368):1278-1283.

Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation. Scholler P, Nevoltris D et al. Nat Commun. 2017 Dec 6;8(1):1967.

Atomic structures of minor proteins VI and VII in the human adenovirus. Dai X, Wu L et al. J Virol. 2017 Dec;91(24):00850-17.

Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras. Xu S, Long BN et al. Acta Crystallogr D Struct Biol. 2017 Dec 1;73(Pt 12):970-984.

3.9 Å structure of the yeast Mec1-Ddc2 complex, a homolog of human ATR-ATRIP. Wang X, Ran T et al. Science. 2017 Dec 1;358(6367):1206-1209.

Structural basis for the initiation of eukaryotic transcription-coupled DNA repair. Xu J, Lahiri I et al. Nature. 2017 Nov 30;551(7682):653-657.

Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster. Holzer S, Yan J et al. Nat Commun. 2017 Nov 23;8(1):1718.

Atomic model for the dimeric F_O region of mitochondrial ATP synthase. Guo H, Bueler SA, Rubinstein JL. Science. 2017 Nov 17;358(6365):936-940.

Structural basis of bacterial transcription activation. Liu B, Hong C et al. Science. 2017 Nov 17;358(6365):947-951.

Structure and assembly of the Ebola virus nucleocapsid. Wan W, Kolesnikova L et al. Nature. 2017 Nov 16;551(7680):394-397.

Customizable de novo design strategies for DOCK: Application to HIVgp41 and other therapeutic targets. Allen WJ, Fochtman BC et al. J Comput Chem. 2017 Nov 15;38(30):2641-2663.

Structural insight into TPX2-stimulated microtubule assembly. Zhang R, Roostalu J et al. eLife. 2017 Nov 9;6. pii: e30959.

Structures of transcription pre-initiation complex with TFIIH and Mediator. Schilbach S, Hantsche M et al. Nature. 2017 Nov 9;551(7679):204-209.

Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing. Puchades C, Rampello AJ et al. Science. 2017 Nov 3;358(6363). pii: eaao0464.

Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo. Ljubetič A, Lapenta F et al. Nat Biotechnol. 2017 Nov;35(11):1094-1101.

Solvatochromism and preferential solvation of Brooker's merocyanine in water-methanol mixtures. Tanaka Y, Kawashima Y et al. J Comput Chem. 2017 Oct 30;38(28):2411-2419.

CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing. Li X, Liu S et al. Nat Commun. 2017 Oct 19;8(1):1035.

Capsids and genomes of jumbo-sized bacteriophages reveal the evolutionary reach of the HK97 fold. Hua J, Huet A et al. MBio. 2017 Oct 17;8(5). pii: e01579-17.

Competing scaffolding proteins determine capsid size during mobilization of Staphylococcus aureus pathogenicity islands. Dearborn AD, Wall EA et al. eLife. 2017 Oct 6;6. pii: e30822.

Conformational entropy as collective variable for proteins. Palazzesi F, Valsson O, Parrinello M. J Phys Chem Lett. 2017 Oct 5;8(19):4752-4756

Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. Guo TW, Bartesaghi A et al. Cell. 2017 Oct 5;171(2):414-426.e12.

Structure of the human mitochondrial ribosome studied in situ by cryoelectron tomography. Englmeier R, Pfeffer S, Förster F. Structure. 2017 Oct 3;25(10):1574-1581.e2.