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Recent Citations

Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase. Verba KA, Wang RY et al. Science. 2016 Jun 24;352(6293):1542-7.

Structure and membrane remodeling activity of ESCRT-III helical polymers. McCullough J, Clippinger AK et al. Science. 2015 Dec 18;350(6267):1548-51.

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News

March 28, 2017

An alpha release of ChimeraX is available (Mac, Linux, Windows). For information on features, please see the documentation.

December 22, 2016

ChimeraX pre-release daily builds are available!

Upcoming Events

June 4 and 7, 2017

Tristan Croll will lead workshop sessions on his ChimeraX plugin ISOLDE (for interactive structure refinement) at the EMBO course on Integrative Structural Biology (June 3-10 in Erice, Italy).


UCSF ChimeraX

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see licensing.

ChimeraX development is funded by the National Institutes of Health (NIGMS P41-GM103311).

Feature Highlight

3w1k assembly 1

Assembly from mmCIF Symmetry Information

Multimeric assemblies defined in a structure's mmCIF file can be listed in the Log and built using the sym command. The complex of selenocysteine synthase and tRNASec (PDB 3w1k) is shown as molecular surfaces of different colors for different chains. The asymmetric unit is on the left and the assembly specified in the mmCIF file is on the right, with arrow and text annotations from 2dlabels. See the command file sym.cxc.

More features...

Example Image

cyclodextrin pore

Cyclodextrin Pore

The outer-membrane protein CymA admits bulky molecules into the periplasmic space of Klebsiella oxytoca. Here, CymA (PDB 4d5d chain A) is depicted in a style reminiscent of a diagnostic X-ray, with transparent molecular surface and β-strand “ribs” in white. The protein has ingested α-cyclodextrin (top) and β-cyclodextrin (bottom), bound at the entry site and near the exit, respectively. Cyclodextrin carbon atoms are shown in blue-gray and oxygen atoms in brick red. For image setup other than orientation, see the command file xray.cxc.

More images...