about projects people publications resources resources visit us visit us search search

Quick Links

Featured Citations

Organizing structural principles of the IL-17 ligand-receptor axis. Wilson SC, Caveney NA et al. Nature. 2022 Sep 15;609(7927):622-629.

Mechanism of AAA+ ATPase-mediated RuvAB-Holliday junction branch migration. Wald J, Fahrenkamp D et al. Nature. 2022 Sep 15;609(7927):630-639.

Membranes under the magnetic lens: A dive into the diverse world of membrane protein structures using cryo-EM. Piper SJ, Johnson RM et al. Chem Rev. 2022 Sep 14;122(17):13989-14017.

R-loop formation and conformational activation mechanisms of Cas9. Pacesa M, Loeff L et al. Nature. 2022 Sep 1;609(7925):191-196.

Molecular architecture of nucleosome remodeling and deacetylase sub-complexes by integrative structure determination. Arvindekar S, Jackman MJ et al. Protein Sci. 2022 Sep;31(9):e4387.

More citations...

News

September 27, 2022

Website downtime: The RBVI website (Chimera, ChimeraX, etc.) and RBVI-hosted web services will be down for maintenance from Tue, Sep 27 9pm PDT, through Wed, possibly extending to Thu, Sep 29 5pm PDT.

June 10, 2022

The ChimeraX 1.4 production release is available. See the change log for what's new. ChimeraX 1.4 is the last release to support macOS 10.14 (Mojave).

May 10, 2022

The ChimeraX 1.4 release candidate is available. Please try it and report any issues. See the change log for what's new. ChimeraX 1.4 is the last release to support macOS 10.14 (Mojave).

Previous news...

Upcoming Events


UCSF ChimeraX

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see ChimeraX commercial licensing.

ChimeraX is developed with support from National Institutes of Health R01-GM129325, Chan Zuckerberg Initiative grant EOSS4-0000000439, and the Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases.

Feature Highlight

3eeb assembly 1 Coulombic ESP coloring

Coulombic Electrostatic Potential

Coulombic electrostatic potential (ESP) can be calculated and displayed with surface coloring using the command coulombic or the Molecule Display icon . No separate calculation or input ESP file is required. The image shows the first assembly defined for PDB 3eeb, the protease domain of a toxin from Vibrio cholerae, with the default Coulombic coloring: red-white-blue over the value range –10 to 10. For image setup other than orientation, see the command file coulombic.cxc.

For how to add a color key and associated label, see the Protein-Ligand Binding Sites tutorial.

More features...

Example Image

HIV-1 protease B-factor coloring

B-factor Coloring

Atomic B-factor values are read from PDB and mmCIF input files and assigned as attributes that can be shown with coloring and used in atom specification. This example shows B-factor variation within a structure of the HIV-1 protease bound to an inhibitor (PDB 4hvp). For complete image setup, including positioning, color key, and label, see the command file bfactor.cxc.

Additional color key examples can be found in tutorials: Coloring by Electrostatic Potential, Coloring by Sequence Conservation

More images...



About RBVI | Projects | People | Publications | Resources | Visit Us

Copyright 2018 Regents of the University of California. All rights reserved.