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Recent Citations

Architecture of the 90S pre-ribosome: A structural view on the birth of the eukaryotic ribosome. Kornprobst M, Turk M et al. Cell. 2016 Jul 14;166(2):380-93.

Cryo-EM structure of a human cytoplasmic actomyosin complex at near-atomic resolution. von der Ecken J, Heissler SM et al. Nature. 2016 Jun 30;534(7609):724-8.

Rational design and validation of a vanilloid-sensitive TRPV2 ion channel. Yang F, Vu S et al. Proc Natl Acad Sci USA. 2016 Jun 28;113(26):E3657-66.

Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase. Verba KA, Wang RY et al. Science. 2016 Jun 24;352(6293):1542-7.

TRPV1 structures in nanodiscs reveal mechanisms of ligand and lipid action. Gao Y, Cao E et al. Nature. 2016 Jun 16;534(7607):347-51.

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Chimera Search

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July 15, 2016

Chimera production release 1.11 is now available. 64-bit builds are now recommended for all capable platforms, and v1.11 will be the last to support 32-bit builds. See the release notes for details.

June 23, 2016

PLOS Computational Biology announces winning T-shirt design created by Luigi Di Costanzo (RCSB Protein Data Bank) using UCSF Chimera.

April 6, 2016

A production release candidate (v1.11) is available; please try it and report any problems. 64-bit builds are now recommended for all capable platforms, and v1.11 will be the last to support 32-bit builds. See the release notes for what's new.

(Previous news...)

Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), funded by the National Institutes of Health (NIGMS P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera. It is in early development and not yet publicly released, with release anticipated sometime in 2016.

Feature Highlight

radial surface color

Radial Coloring

A surface can be colored radially, that is, by distance from a user-specified point. Additional options include coloring by distance from an axis or a plane. Different coloring schemes can be applied.

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Gallery Sample

Peroxiredoxin Wreath

Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.

See also the RBVI holiday card gallery.

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