Structure of the herpes simplex virus 1 capsid with associated tegument protein complexes. Dai X, Zhou ZH. Science. 2018 Apr 6;360(6384). pii: eaao7298.
Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule. Tsai JC, Miller-Vedam LE et al. Science. 2018 Mar 30;359(6383).
Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B. Zyryanova AF, Weis F et al. Science. 2018 Mar 30;359(6383):1533-1536.
EF-Tu and EF-G are activated by allosteric effects. Mondal D, Warshel A. Proc Natl Acad Sci USA. 2018 Mar 27;115(13):3386-3391.
Ligand binding site structure influences the evolution of protein complex function and topology. Abrusán G, Marsh JA. Cell Rep. 2018 Mar 20;22(12):3265-3276.(Previously featured citations...)
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For a nice 3D-printing protocol that uses Chimera, see 3D Printing of Biomolecular Models for Research and Pedagogy by Da Veiga Beltrame, Tyrwhitt-Drake, et al. today in JoVE!(Previous news...)
UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), supported in part by the National Institutes of Health (NIGMS P41-GM103311).
UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.
Space Navigator is an inexpensive ($60) USB input device from 3Dconnexion for moving and rotating models in 3 dimensions. This animation (8 Mb) shows docking a phage enzyme (PDB 1v0e) into an electron microscopy map (EMDB 1333) using a space navigator and mouse. Works with Windows and Mac Chimera versions (details).(More features...)