about projects people publications resources resources visit us visit us search search

Quick Links

Recent Citations

Structural basis for the modulation of voltage-gated sodium channels by animal toxins. Shen H, Li Z et al. Science. 2018 Oct 19;362(6412). pii: eaau2596.

Structure and dynamics of the yeast SWR1-nucleosome complex. Willhoft O, Ghoneim M et al. Science. 2018 Oct 12;362(6411). pii: eaat7716.

A viral protein restricts Drosophila RNAi immunity by regulating Argonaute activity and stability. Nayak A, Kim DY et al. Cell Host Microbe. 2018 Oct 10;24(4):542-557.e9.

High-resolution structures of HIV-1 Gag cleavage mutants determine structural switch for virus maturation. Mattei S, Tan A et al. Proc Natl Acad Sci USA. 2018 Oct 2;115(40):E9401-E9410.

Structural basis for activation of voltage sensor domains in an ion channel TPC1. Kintzer AF, Green EM et al. Proc Natl Acad Sci USA. 2018 Sep 25;115(39):E9095-E9104.

(Previously featured citations...)

Chimera Search

Google™ Search

News

September 21, 2018

Mac users are advised to hold off upgrading to Mojave until we find a fix for Chimera buttons not being shown until the windows containing them are resized.

July 3, 2018

Chimera production release 1.13 is now available. See the release notes for what's new.

June 2, 2018

A production release candidate (version 1.13) is available; please try it and report any problems. See the release notes for what's new.

(Previous news...)

Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), supported in part by the National Institutes of Health (P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

1le4 sequence

Annotations from UniProt

The PDB/UniProt Info tool retrieves sequence and structure annotations for Protein Data Bank (PDB) entries using a Web service provided by the RCSB PDB. Sequences are displayed in Multalign Viewer, and feature annotations from UniProt are mapped onto the sequences as regions or colored boxes. In the region browser (figure at right):

  • making a region Active selects any corresponding structure residues for further operations; only one region can be active at a time
  • making a region Shown displays it in the sequence window
  • the square color wells show (and allow changing) the region interior and border colors
UniProt annotations can also be fetched along with a sequence or mapped to a sequence already in Multalign Viewer regardless of whether the sequence is associated with a structure.

(More features...)

Gallery Sample

Clathrin

This image of a clathrin cage uses flat shading and edge highlighting. It is a copy of a PDB molecule of the month image made by Graham Johnson and Dave Goodsell. David Goodsell pioneered this visualization style. This image was made with the Multiscale tool, silhouette edging, and surface lighting turned off.

Protein Data Bank model 1xi4.

(More samples...)


About RBVI | Projects | People | Publications | Resources | Visit Us

Copyright 2018 Regents of the University of California. All rights reserved.