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SlyB encapsulates outer membrane proteins in stress-induced lipid nanodomains. Janssens A, Nguyen VS et al. Nature. 2024 Feb 15;626(7999):617–625.

Characterization and heterologous reconstitution of Taxus biosynthetic enzymes leading to baccatin III. Jiang B, Gao L et al. Science. 2024 Feb 9;383(6683):622-629.

Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127. Montoya S, Bourcier J et al. Science. 2024 Feb 2;383(6682):eadi5798.

Enhancer-driven 3D chromatin domain folding modulates transcription in human mammary tumor cells. Kocanova S, Raynal F et al. Life Sci Alliance. 2024 Feb;7(2):e202302154.

Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Kumar N, Sharma S, Kaushal PS. Nat Commun. 2024 Jan 20;15(1):638.

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October 30-31, 2023

Planned downtime: The Chimera and ChimeraX websites and associated web services will be unavailable Oct 30 8am PDT – Oct 31 11:59pm PDT.

April 19, 2023

Chimera production release 1.17.1 is now available, fixing an issue with 1.17 for Windows and Linux. See the release notes for details.

April 13, 2023

Chimera production release 1.17 is now available. Updating is required to keep using the tools that run Blast Protein, Modeller, and multiple sequence alignment with Clustal Omega or MUSCLE, as these will soon stop working in older versions. See the release notes for details.

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Upcoming Events

Please note that UCSF Chimera is legacy software that is no longer being developed or supported. Users are strongly encouraged to try UCSF ChimeraX, which is under active development.

UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.

We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features in addition to nearly all the capabilities of Chimera (details...).

Chimera is no longer under active development. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.

Feature Highlight

radial surface color

Radial Coloring

A surface can be colored radially, that is, by distance from a user-specified point. Additional options include coloring by distance from an axis or a plane. Different coloring schemes can be applied.

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Gallery Sample

Peroxiredoxin Wreath

Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.

See also the RBVI holiday card gallery.

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