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Recent Citations

The path of pre-ribosomes through the nuclear pore complex revealed by electron tomography. Delavoie F, Soldan V et al. Nat Commun. 2019 Jan 30;10(1):497.

FGF21 trafficking in intact human cells revealed by cryo-electron tomography with gold nanoparticles. Azubel M, Carter SD et al. eLife. 2019 Jan 28;8. pii: e43146.

Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus. Whitesell L, Robbins N et al. Nat Commun. 2019 Jan 24;10(1):402.

GABAA receptor signalling mechanisms revealed by structural pharmacology. Masiulis S, Desai R et al. Nature. 2019 Jan 24;565(7740):454-459.

Chemical cross-linking enables drafting ClpXP proximity maps and taking snapshots of in situ interaction networks. Fux A, Korotkov VS et al. Cell Chem Biol. 2019 Jan 17;26(1):48-59.e7.

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Chimera Search

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November 17, 2018

Chimera production release 1.13.1 is now available; see the release notes for what's new. The Mac version requires OS 10.10 or later.

October 22, 2018

Mac users: the 1.13.1 release candidate and recent daily builds contain a fix for Mojave (OS 10.14). These versions require OS 10.10 or later.

September 21, 2018

Mac users are advised to hold off upgrading to Mojave until we find a fix for Chimera buttons not being shown until the windows containing them are resized.

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Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), supported in part by the National Institutes of Health (P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

Interactive Shadows

Interactive shadows (shadows that move as structures are moved) can be enabled in the Effects dialog or with the command set shadows. Click the image to show a small molecule rotating above a rectangular plane. This simple animation was made with the Chimera command script tumble.com. Interactive shadows also work with ribbons, surfaces, and other representations.

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Gallery Sample

Peroxiredoxin Wreath

Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.

See also the RBVI holiday card gallery.

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