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Structural basis of sodium-dependent bile salt uptake into the liver. Goutam K, Ielasi FS et al. Nature. 2022 Jun 30;606(7916):1015-1020.
Structural basis of GABA reuptake inhibition. Motiwala Z, Aduri NG et al. Nature. 2022 Jun 23;606(7915):820-826.
Structure of the mammalian ribosome as it decodes the selenocysteine UGA codon. Hilal T, Killam BY et al. Science. 2022 Jun 17;376(6599):1338-1343.
Structure of the cytoplasmic ring of the Xenopus laevis nuclear pore complex. Zhu X, Huang G et al. Science. 2022 Jun 10;376(6598):eabl8280.
Architecture of the cytoplasmic face of the nuclear pore. Bley CJ, Nie S et al. Science. 2022 Jun 10;376(6598):eabm9129.
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December 20, 2021
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December 17, 2021
Chimera production release 1.16 is now available. This will be the last release to support Windows 7. See the release notes for what's new.
December 18, 2020
Chimera production release 1.15 is now available. See the release notes for what's new.
(Previous news...)Upcoming Events
UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.
We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features. ChimeraX includes a significant subset of Chimera features (with more to come, see the missing features list) and is under active development. Users may choose to use both programs, and it is fine to have both installed.
Chimera is no longer under active development, and is only updated for critical maintenance. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.
Feature Highlight
The fly command can animate a flight through molecular structures. Click the example image to fly along the RNA being copied by rotavirus RNA polymerase (PDB 2r7r), an enzyme that replicates the 11 segments of viral RNA. See a video showing how this animation was made.
(More features...)Gallery Sample
Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.
See also the RBVI holiday card gallery.
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