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Recent Citations

A molecular pore spans the double membrane of the coronavirus replication organelle. Wolff G, Limpens RWAL et al. Science. 2020 Sep 11;369(6509):1395-1398.

Structural basis of transcription-translation coupling. Wang C, Molodtsov V et al. Science. 2020 Sep 11;369(6509):1359-1365.

Shared structural mechanisms of general anaesthetics and benzodiazepines. Kim JJ, Gharpure A et al. Nature. 2020 Sep 10;585(7824):303–308.

Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD. Su MY, Fromm SA et al. Nature. 2020 Sep 10;585(7824):251–255.

Irritant-evoked activation and calcium modulation of the TRPA1 receptor. Zhao J, Lin King JV et al. Nature. 2020 Sep 3;585(7823):141-145.

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November 13, 2019

Chimera production release 1.14 is now available. See the release notes for what's new.

September 21, 2019

A production release candidate (version 1.14) is available; please try it and report any problems. See the release notes for what's new.

November 17, 2018

Chimera production release 1.13.1 is now available; see the release notes for what's new. The Mac version requires OS 10.10 or later.

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Upcoming Events

UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. High-quality images and animations can be generated. Chimera includes complete documentation and is free of charge for academic, government, nonprofit, and personal use. Chimera development was supported by the National Institutes of Health (P41-GM103311).

UCSF ChimeraX is the next-generation molecular visualization program from the RBVI, following UCSF Chimera. We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages. ChimeraX replaces a significant subset of Chimera features, includes several completely new features, and is under active development. Users may certainly choose to use both programs, and it is fine to have both installed.

Feature Highlight

DNA and netropsin

Molecular Graphics

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Gallery Sample

Annotated Green Fluorescent Protein

BILD format was used in Chimera to annotate the barrel structure of green fluorescent protein with its centroid, major axis (red arrow), and an enclosing cylinder (shown with green hoops). The BILD file green.bild was generated with the python program green.py using the coordinates in green.pdb. Gallery entry courtesy of Mike Ess, Yeast Resource Center, University of Washington. (More samples...)

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