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Recent Citations

Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex. Lawrence RE, Fromm SA et al. Science. 2019 Nov 22;366(6468):971-977.

Structure of the mitochondrial import gate reveals distinct preprotein paths. Araiso Y, Tsutsumi A et al. Nature. 2019 Nov 14;575(7782):395-401.

Scaffold subunits support associated subunit assembly in the Chlamydomonas ciliary nexin-dynein regulatory complex. Gui L, Song K et al. Proc Natl Acad Sci USA. 2019 Nov 12;116(46):23152-23162.

Calculation of absolute binding free energies between the hERG channel and structurally diverse drugs. Negami T, Araki M et al. Sci Rep. 2019 Nov 12;9(1):16586.

Drivers of α-sheet formation in transthyretin under amyloidogenic conditions. Childers MC, Daggett V. Biochemistry. 2019 Nov 5;58(44):4408-4423.

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News

November 13, 2019

Chimera production release 1.14 is now available. See the release notes for what's new.

September 21, 2019

A production release candidate (version 1.14) is available; please try it and report any problems. See the release notes for what's new.

November 17, 2018

Chimera production release 1.13.1 is now available; see the release notes for what's new. The Mac version requires OS 10.10 or later.

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Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), supported in part by the National Institutes of Health (P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

surface color by density

Coloring by Density

A surface can be colored by density or other volume data. In the image, the surface is clipped and capped, and only the cap is colored by density. Different coloring schemes can be applied.

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Gallery Sample

Cavity and Tunnel Detection

Side-by-side views of a potassium channel structure (Protein Data Bank entry 1bl8) showing different approaches to cavity detection. On the left are molecular surface patches corresponding to the structure's two largest pockets by MS volume in the Computed Atlas of Surface Topography of proteins (CASTp) database. On the right is a tunnel in blue identified by the MolAxis server. Simple editing converted MolAxis output into a BILD file for display in Chimera. (More samples...)


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