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Recent Citations

Structure of Hsp90-Hsp70-Hop-GR reveals the Hsp90 client-loading mechanism. Wang RY, Noddings CM et al. Nature. 2022 Jan 20;601(7893):460–464.

Structure and mechanism of the SGLT family of glucose transporters. Han L, Qu Q et al. Nature. 2022 Jan 13;601(7892):274–279.

Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex. Patil DN, Singh S et al. Science. 2022 Jan 7;375(6576):86-91.

Leveraging crosslinking mass spectrometry in structural and cell biology. Graziadei A, Rappsilber J. Structure. 2022 Jan 6;30(1):37-54.

Integrative structural modeling of macromolecular complexes using Assembline. Rantos V, Karius K, Kosinski J. Nat Protoc. 2022 Jan;17(1):152-176.

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News

December 17, 2021

Chimera production release 1.16 is now available. This will be the last release to support Windows 7. See the release notes for what's new.

December 18, 2020

Chimera production release 1.15 is now available. See the release notes for what's new.

December 11, 2020

The RBVI wishes you a safe and happy holiday season! See our 2020 card and the gallery of previous cards back to 1985.

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Upcoming Events

UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.

We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features. ChimeraX includes a significant subset of Chimera features (with more to come, see the missing features list) and is under active development. Users may choose to use both programs, and it is fine to have both installed.

Chimera is no longer under active development, and is only updated for critical maintenance. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.

Feature Highlight

DNA and netropsin

Molecular Graphics

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Gallery Sample

Clathrin

This image of a clathrin cage uses flat shading and edge highlighting. It is a copy of a PDB molecule of the month image made by Graham Johnson and Dave Goodsell. David Goodsell pioneered this visualization style. This image was made with the Multiscale tool, silhouette edging, and surface lighting turned off.

Protein Data Bank model 1xi4.

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