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Recent Citations

Structure and inhibition of EV-D68, a virus that causes respiratory illness in children. Liu Y, Sheng J et al. Science. 2015 Jan 2;347(6217):71-4.

Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains. Shen PS, Park J et al. Science. 2015 Jan 2;347(6217):75-8.

Structure of a mammalian ryanodine receptor. Zalk R, Clarke OB et al. Nature. 2015 Jan 1;517(7532):44-9.

cddApp: A Cytoscape app for accessing the NCBI Conserved Domain Database. Morris JH, Wu A et al. Bioinformatics. 2015 Jan 1;31(1):134-6.

Does topology drive fiber polymerization? Huang L, Hsiao JP et al. Biochemistry. 2014 Dec 16;53(49):7824-34.

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News

January 9, 2015

Chimera production release 1.10.1 is now available. 64-bit builds are recommended for all capable platforms, and the 1.10 series will be the last to support OS X 10.6 and 10.7. See the release notes for details.

November 5, 2014

Chimera production release 1.10 is now available. 64-bit builds are recommended for all capable platforms, and v1.10 will be the last to support OS X 10.6 and 10.7. See the release notes for what's new.

October 23, 2014

A production release candidate (v1.10) is available; please try it and report any problems. 64-bit builds are now recommended for all capable platforms, and v1.10 will be the last to support OS X 10.6 and 10.7. See the release notes for what's new.

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Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics, funded by the National Institutes of Health (NIGMS P41-GM103311).

Feature Highlight

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image background

Special Backgrounds

The background of the Chimera graphics window can be set to a single solid color, a vertical gradient of multiple colors, or an image read from a file. These and related parameters can be controlled with the command background or in the Background section of the preferences.

Gradients may contain any number of colors, and can be shown as discrete bands or interpolated in the RBG or HLS color space; they can be created, previewed, and named using the Palette Editor. Background images can be cropped, stretched, centered, or tiled. Image formats include PNG, TIFF, and JPEG.

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Gallery Sample

Thermosome

Thermosomes are hollow balls inside which proteins are folded. They are found in the cytosol of eukaryotes and in archaea. Eukaryotic thermosomes have 8 different protein subunits, while archaeal ones are composed of one, two or three different proteins. The one shown from Thermoplasma acidophilum has two distinct proteins colored blue and yellow, each present in 8 copies. The two proteins have 60% sequence identity and are very similar in structure. One monomer is shown as a ribbon. Actin and tubulin are folded by eukaryotic thermosomes.

Protein Data Bank model 1a6d.

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