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Recent Citations

A molecular ruler determines the repeat length in eukaryotic cilia and flagella. Oda T, Yanagisawa H et al. Science. 2014 Nov 14;346(6211):857-60.

Drug sensing by the ribosome induces translational arrest via active site perturbation. Arenz S, Meydan S et al. Mol Cell. 2014 Nov 6;56(3):446-52.

Allosteric signalling in the outer membrane translocation domain of PapC usher. Farabella I, Pham T et al. eLife. 2014 Oct 28;3.

Molecular basis for the ribosome functioning as an L-tryptophan sensor. Bischoff L, Berninghausen O, Beckmann R. Cell Rep. 2014 Oct 23;9(2):469-75.

Structural mechanism of glutamate receptor activation and desensitization. Meyerson JR, Kumar J et al. Nature. 2014 Oct 16;514(7522):328-34.

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Chimera Search

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News

November 5, 2014

Chimera production release 1.10 is now available. 64-bit builds are recommended for all capable platforms, and v1.10 will be the last to support OS X 10.6 and 10.7. See the release notes for what's new.

October 23, 2014

A production release candidate (v1.10) is available; please try it and report any problems. 64-bit builds are now recommended for all capable platforms, and v1.10 will be the last to support OS X 10.6 and 10.7. See the release notes for what's new.

August 15, 2014

We are delighted to announce the publication of a new book, Computational and Visualization Techniques for Structural Bioinformatics Using Chimera, written by Forbes J. Burkowski (University of Waterloo).

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Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics, funded by the National Institutes of Health (NIGMS P41-GM103311).

Feature Highlight

pipes & planks

Pipes and Planks

The PipesAndPlanks tool shows protein helices as “pipes” (cylinders) and strands as “planks” (rectangular boxes), with connectors for the intervening coil. Adjustable settings include pipe radius, plank width, colors, and whether to include arrowheads to show chain N→C directionality (see image how-to).

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Gallery Sample

Sliced Potassium Channel

Potassium channel (Protein Data Bank entry 1bl8) on a dark slate blue background with potassium ions shown in firebrick. The channel is comprised of four chains. Each chain has been rainbow-colored from blue at the N-terminus to red at the C-terminus, but only the surface of the channel is shown. The surface has been sliced with a per-model clipping plane. The surface cap color is plum except with opacity set to 0.8. The shininess and brightness have been set to 128 and 8, respectively, and the lights on the scene have been moved from their default positions. The subdivision quality (related to the smoothness of the spherical ions) is 5.0, and the molecular surface was computed with probe radius and vertex density set to 1.0 and 6.0, respectively. (More samples...)