Reconfiguration of the proteasome during chaperone-mediated assembly. Park S, Li X et al. Nature. 2013 May 23;497:512–6.
Rational HIV immunogen design to target specific germline B cell receptors. Jardine J, Julien JP et al. Science. 2013 May 10;340(6133):711-6.
Self-assembling cages from coiled-coil peptide modules. Fletcher JM, Harniman RL et al. Science. 2013 May 3;340(6132):595-9.
A conformational switch in HP1 releases auto-inhibition to drive heterochromatin assembly. Canzio D, Liao M et al. Nature. 2013 Apr 18;496(7445):377-81.
The bacterial DnaC helicase loader is a DnaB ring breaker. Arias-Palomo E, O'Shea VL et al. Cell. 2013 Apr 11;153(2):438-48.(Previously featured citations...)
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A production release candidate (version 1.7) is now available; please try it and report any problems. See the release notes for changes relative to the previous release. Mac PowerPC and OS X 10.5 are no longer supported.(Previous news...)
UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics, funded by the National Institutes of Health (NIGMS P41-GM103311).
The ConSurf Server provides results as Chimera Web data; after browser configuration, a single click displays the color-coded query structure and multiple sequence alignment with phylogenetic tree and custom headers in a locally installed copy of Chimera (details).
Special thanks to Elana Erez and the Ben-Tal and Pupko groups at Tel Aviv University, and to Fabian Glaser at the Technion.(More features...)
The image shows tetramers of influenza neuraminidase (Protein Data Bank entry 3k3a) styled as flowers. Three tetramers are colored pink, with a central metal ion in white and nearby residues in yellow, and a fourth tetramer is colored green to resemble leaves. Each monomer or “petal” is a six-bladed β-propeller. (More samples...)