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Recent Citations

An electron transfer path connects subunits of a mycobacterial respiratory supercomplex. Gong H, Li J et al. Science. 2018 Nov 30;362(6418). pii: eaat8923.

Binding of histamine to the H1 receptor – a molecular dynamics study. Söldner CA, Horn AHC, Sticht H. J Mol Model. 2018 Nov 29;24(12):346.

Folding pathway of an Ig domain is conserved on and off the ribosome. Tian P, Steward A et al. Proc Natl Acad Sci USA. 2018 Nov 27;115(48):E11284-E11293.

Tracing whale myoglobin evolution by resurrecting ancient proteins. Isogai Y, Imamura H et al. Sci Rep. 2018 Nov 15;8(1):16883.

Conformational transitions of the serotonin 5-HT3 receptor. Polovinkin L, Hassaine G et al. Nature. 2018 Nov 8;563(7730):275-279.

(Previously featured citations...)

Chimera Search

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November 17, 2018

Chimera production release 1.13.1 is now available; see the release notes for what's new. The Mac version requires OS 10.10 or later.

October 22, 2018

Mac users: the 1.13.1 release candidate and recent daily builds contain a fix for Mojave (OS 10.14). These versions require OS 10.10 or later.

September 21, 2018

Mac users are advised to hold off upgrading to Mojave until we find a fix for Chimera buttons not being shown until the windows containing them are resized.

(Previous news...)

Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), supported in part by the National Institutes of Health (P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

phosphomannomutase morphing animation


Different conformations and even different proteins can be compared by morphing from one structure to another. Users can specify the method of coordinate interpolation and how many intermediate structures should be generated. The result is displayed in Chimera's trajectory viewer, MD Movie. The morph can then be saved in coordinate form or recorded as an animation.

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Gallery Sample

Loop Interactions

The image shows interactions of the delta-1 loop with the rest of hepatitis C virus RNA-dependent RNA polymerase (Protein Data Bank entry 1quv). Loop residues in contact with the rest of the structure (van der Waals overlap ≥ 0.01 Å) are displayed as sticks; interacting surface atoms are shown as red patches. (More samples...)

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