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Recent Citations

Structure of the posttranslational Sec protein-translocation channel complex from yeast. Itskanov S, Park E. Science. 2019 Jan 4;363(6422):84-87.

Structures of TRPV2 in distinct conformations provide insight into role of the pore turret. Dosey TL, Wang Z et al. Nat Struct Mol Biol. 2019 Jan;26(1):40-49.

Polarized displacement by transcription activator-like effectors for regulatory circuits. Lebar T, Verbič A et al. Nat Chem Biol. 2019 Jan;15(1):80-87.

Structure of human TFIID and mechanism of TBP loading onto promoter DNA. Patel AB, Louder RK et al. Science. 2018 Dec 21;362(6421). pii: eaau8872.

Structure of native lens connexin 46/50 intercellular channels by cryo-EM. Myers JB, Haddad BG et al. Nature. 2018 Dec 20;564(7736):372-377.

(Previously featured citations...)

Chimera Search

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November 17, 2018

Chimera production release 1.13.1 is now available; see the release notes for what's new. The Mac version requires OS 10.10 or later.

October 22, 2018

Mac users: the 1.13.1 release candidate and recent daily builds contain a fix for Mojave (OS 10.14). These versions require OS 10.10 or later.

September 21, 2018

Mac users are advised to hold off upgrading to Mojave until we find a fix for Chimera buttons not being shown until the windows containing them are resized.

(Previous news...)

Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), supported in part by the National Institutes of Health (P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

volume plane display

Volume Plane Display

Volume data can be shown a single plane (or slab) at a time with the Planes feature in Volume Viewer. Plane display can be set to oscillate along the data X, Y, or Z axis, or the plane location can be specified interactively with a slider.

(More features...)

Gallery Sample

Cavity and Tunnel Detection

Side-by-side views of a potassium channel structure (Protein Data Bank entry 1bl8) showing different approaches to cavity detection. On the left are molecular surface patches corresponding to the structure's two largest pockets by MS volume in the Computed Atlas of Surface Topography of proteins (CASTp) database. On the right is a tunnel in blue identified by the MolAxis server. Simple editing converted MolAxis output into a BILD file for display in Chimera. (More samples...)

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