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Recent Citations

GaudiMM: A modular multi-objective platform for molecular modeling. Rodríguez-Guerra Pedregal J, Sciortino G et al. J Comput Chem. 2017 Sep 15;38(24):2118-2126.

Lis1 has two opposing modes of regulating cytoplasmic dynein. DeSantis ME, Cianfrocco MA et al. Cell. 2017 Sep 7;170(6):1197-1208.e12.

Structures of Medicago truncatula L-histidinol dehydrogenase show rearrangements required for NAD+ binding and the cofactor positioned to accept a hydride. Ruszkowski M, Dauter Z. Sci Rep. 2017 Sep 5;7(1):10476.

Differential replication of foot-and-mouth disease viruses in mice determine lethality. Cacciabue M, García-Núñez MS et al. Virology. 2017 Sep;509:195-204.

Katanin spiral and ring structures shed light on power stroke for microtubule severing. Zehr E, Szyk A et al. Nat Struct Mol Biol. 2017 Sep;24(9):717-725.

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News

September 12, 2017

A production release candidate (version 1.12) is available; please try it and report any problems. See the release notes for what's new.

March 13, 2017

For a nice 3D-printing protocol that uses Chimera, see 3D Printing of Biomolecular Models for Research and Pedagogy by Da Veiga Beltrame, Tyrwhitt-Drake, et al. today in JoVE!

December 2, 2016

Chimera production release 1.11.2 is now available. This version has been updated to work with changes in NCBI Blast and to avoid crashes on Mac Sierra (see the release notes for details).

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Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), funded by the National Institutes of Health (NIGMS P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

Space Navigator demonstration

Space Navigator Input Device

Space Navigator is an inexpensive ($60) USB input device from 3Dconnexion for moving and rotating models in 3 dimensions. This animation (8 Mb) shows docking a phage enzyme (PDB 1v0e) into an electron microscopy map (EMDB 1333) using a space navigator and mouse. Works with Windows and Mac Chimera versions (details).

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Gallery Sample

Clathrin

This image of a clathrin cage uses flat shading and edge highlighting. It is a copy of a PDB molecule of the month image made by Graham Johnson and Dave Goodsell. David Goodsell pioneered this visualization style. This image was made with the Multiscale tool, silhouette edging, and surface lighting turned off.

Protein Data Bank model 1xi4.

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