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Recent Citations

A viral RNA hijacks host machinery using dynamic conformational changes of a tRNA-like structure. Bonilla SL, Sherlock ME et al. Science. 2021 Nov 19;374(6570):955-960.

AKIRIN2 controls the nuclear import of proteasomes in vertebrates. de Almeida M, Hinterndorfer M et al. Nature. 2021 Nov 18;599(7885):491-496.

Dispatched uses Na+ flux to power release of lipid-modified Hedgehog. Wang Q, Asarnow DE et al. Nature. 2021 Nov 11;599(7884):320-324.

Kainate receptor modulation by NETO2. He L, Sun J et al. Nature. 2021 Nov 11;599(7884):325-329.

Mapping the catalytic conformations of an assembly-line polyketide synthase module. Cogan DP, Zhang K et al. Science. 2021 Nov 5;374(6568):729-734.

(Previously featured citations...)

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News

December 18, 2020

Chimera production release 1.15 is now available. See the release notes for what's new.

December 11, 2020

The RBVI wishes you a safe and happy holiday season! See our 2020 card and the gallery of previous cards back to 1985.

November 4, 2020

A 1.15 production release candidate is available, including a fix to work with the new PDB fetch locations (see the release notes). Please try it and report any problems.

(Previous news...)

Upcoming Events

UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.

We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features. ChimeraX includes a significant subset of Chimera features (with more to come, see the missing features list) and is under active development. Users may choose to use both programs, and it is fine to have both installed.

Chimera is no longer under active development, and is only updated for critical maintenance. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.

Feature Highlight

Space Navigator demonstration

Space Navigator Input Device

Space Navigator is an inexpensive ($60) USB input device from 3Dconnexion for moving and rotating models in 3 dimensions. This animation (8 Mb) shows docking a phage enzyme (PDB 1v0e) into an electron microscopy map (EMDB 1333) using a space navigator and mouse. Works with Windows and Mac Chimera versions (details).

(More features...)

Gallery Sample

Sliced Potassium Channel

Potassium channel (Protein Data Bank entry 1bl8) on a dark slate blue background with potassium ions shown in firebrick. The channel is comprised of four chains. Each chain has been rainbow-colored from blue at the N-terminus to red at the C-terminus, but only the surface of the channel is shown. The surface has been sliced with a per-model clipping plane. The surface cap color is plum except with opacity set to 0.8. The shininess and brightness have been set to 128 and 8, respectively, and the lights on the scene have been moved from their default positions. The subdivision quality (related to the smoothness of the spherical ions) is 5.0, and the molecular surface was computed with probe radius and vertex density set to 1.0 and 6.0, respectively. (More samples...)


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