home overview research resources outreach & training outreach & training visitors center visitors center search search

Quick Links

Recent Citations

Accuracy analysis of multiple structure alignments. Berbalk C, Schwaiger CS, Lackner P. Protein Sci. 2009 Oct;18(10):2027-35.

10-Å cryoEM structure and molecular model of the Myriapod (Scutigera) 6x6mer hemocyanin: understanding a giant oxygen transport protein. Markl J, Moeller A et.al. J Mol Biol. 2009 Sep 18;392(2):362-80.

Structural changes to monomeric CuZn superoxide dismutase caused by the familial amyotrophic lateral sclerosis-associated mutation A4V. Schmidlin T, Kennedy BK, Daggett V. Biophys J. 2009 Sep 16;97(6):1709-18.

A dimeric structure for archaeal box C/D small ribonucleoproteins. Bleichert F, Gagnon KT et.al. Science. 2009 Sep 11;325(5946):1384-7.

Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy. Wang L, Sigworth FJ. Nature. 2009 Sep 10;461(7261):292-5.

(Previously featured citations...)

Chimera Search

Google™ Search

News

October 14, 2009

A new Chimera production release candidate (version 1.4) is now available. Many new features have been added since the last production release. Please try the release candidate and report any problems.

August 20, 2009

A new Chimera snapshot release is available. This release provides access to many new features added since the last production release, with a greater level of testing than daily builds.

July 3, 2009

SMILES → 3D conversion and fetching modeled 3D structures by PubChem CID have been updated (in daily builds) to use the new REST services provided by the Chemical Informatics and Cyberinfrastructure Collaboratory (CICC) at Indiana University.

(Previous news...)

Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics and funded by the NIH National Center for Research Resources (grant P41-RR01081).

Feature Highlight

Consurf coloring and alignment

Showing ConSurf Results

The ConSurf Server provides results as Chimera Web data; after browser configuration, a single click displays the color-coded query structure and multiple sequence alignment with phylogenetic tree and custom headers in a locally installed copy of Chimera (details).

Special thanks to Elana Erez and the Ben-Tal and Pupko groups at Tel Aviv University, and to Fabian Glaser at the Technion.

(More features...)

Gallery Sample

Thermosome

Thermosomes are hollow balls inside which proteins are folded. They are found in the cytosol of eukaryotes and in archaea. Eukaryotic thermosomes have 8 different protein subunits, while archaeal ones are composed of one, two or three different proteins. The one shown from Thermoplasma acidophilum has two distinct proteins colored blue and yellow, each present in 8 copies. The two proteins have 60% sequence identity and are very similar in structure. One monomer is shown as a ribbon. Actin and tubulin are folded by eukaryotic thermosomes.

Protein Data Bank model 1a6d.

(More samples...)