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Recent Citations

Structures of the human Mediator and Mediator-bound preinitiation complex. Chen X, Yin X et al. Science. 2021 Jun 4;372(6546):eabg0635.

Control of distal lysine coordination in a monomeric hemoglobin: A role for heme peripheral interactions. Martinez Grundman JE, Julió Plana L et al. J Inorg Biochem. 2021 Jun;219:111437.

Structure reveals the activation mechanism of the MC4 receptor to initiate satiation signaling. Israeli H, Degtjarik O et al. Science. 2021 May 21;372(6544):808-814.

Structures of telomerase at several steps of telomere repeat synthesis. He Y, Wang Y et al. Nature. 2021 May 20;593(7859):454-459.

Mechanosensitive channel YnaI has lipid-bound extended sensor paddles. Hu W, Wang Z, Zheng H. Commun Biol. 2021 May 20;4(1):602.

(Previously featured citations...)

Chimera Search

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May 6, 2021

We're looking for somebody to join the ChimeraX development team! Please see the job posting for details.

December 18, 2020

Chimera production release 1.15 is now available. See the release notes for what's new.

December 11, 2020

The RBVI wishes you a safe and happy holiday season! See our 2020 card and the gallery of previous cards back to 1985.

(Previous news...)

Upcoming Events

UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.

We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features. ChimeraX includes a significant subset of Chimera features (with more to come, see the missing features list) and is under active development. Users may choose to use both programs, and it is fine to have both installed.

Chimera is no longer under active development, and is only updated for critical maintenance. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.

Feature Highlight

EM map morph

Morphing Density Maps

Related density maps can be compared by morphing from one to the other. Several intermediate maps are generated by interpolating between the starting and ending maps. The morph can be viewed interactively and recorded as a movie. The contour level can be adjusted automatically to keep the enclosed volume constant throughout the morph, and other aspects of map display can be adjusted with Volume Viewer.

(More features...)

Gallery Sample

Wasabi Receptor

The image shows the structure of the human TRPA1 ion channel (wasabi receptor) determined by electron cryo-microscopy, Protein Data Bank entry 3j9p. The four subunits of the tetramer are shown as ribbons in different colors over a dark-to-light gradient background. (More samples...)

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