home overview research resources outreach & training outreach & training visitors center visitors center search search

Quick Links

Recent Citations

Cryo-EM structure of human adenovirus D26 reveals the conservation of structural organization among human adenoviruses. Yu X, Veesler D et al. Sci Adv. 2017 May 10;3(5):e1602670.

Relation between molecular electronic structure and nuclear spin-induced circular dichroism. Štěpánek P, Coriani S et al. Sci Rep. 2017 Apr 24;7:46617.

Architecture of a transcribing-translating expressome. Kohler R, Mooney RA et al. Science. 2017 Apr 14;356(6334):194-197.

Mediator structure and rearrangements required for holoenzyme formation. Tsai KL, Yu X et al. Nature. 2017 Apr 13;544(7649):196-201.

PLP and GABA trigger GabR-mediated transcription regulation in Bacillus subtilis via external aldimine formation. Wu R, Sanishvili R et al. Proc Natl Acad Sci USA. 2017 Apr 11;114(15):3891-3896.

(Previously featured citations...)

Chimera Search

Google™ Search


December 2, 2016

Chimera production release 1.11.2 is now available. This version has been updated to work with changes in NCBI Blast and to avoid crashes on Mac Sierra (see the release notes for details).

September 24, 2016

Production release candidate (version 1.11.2) is available, superseding 1.11.1. The new version has been updated to work with changes in NCBI Blast (see release notes). Please try it and report any problems.

August 27, 2016

A production release candidate (version 1.11.1) is now available. Please try it and report any problems. See the release notes for what's been fixed since 1.11. The 1.11 release series will be the last to support 32-bit builds.

(Previous news...)

Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), funded by the National Institutes of Health (NIGMS P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

Screening Docked Molecules

View Dock image

Given the structures of ligand and receptor molecules, docking programs calculate possible binding modes. In virtual screening, small organic compounds (typically from a database of many thousands) are treated as possible ligands, and a target macromolecule is treated as the receptor.

ViewDock facilitates the interactive selection of compounds from the output of docking programs, including DOCK and Maestro/Glide. The hits can be viewed in the context of the binding site and sorted or screened by various properties such as score or number of hydrogen bonds to the receptor. The Dock Prep tool can be used to prepare structures for docking or other calculations by adding hydrogens, assigning partial charges, and performing other related tasks.

(More features...)

Gallery Sample

Peroxiredoxin Wreath

Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath.

See also the RBVI holiday card gallery.

(More samples...)