about projects people publications resources resources visit us visit us search search

Quick Links

Featured Citations

Structure of the ATP-driven methyl-coenzyme M reductase activation complex. Ramírez-Amador F, Paul S et al. Nature. 2025 Jun 19;642(8068):814–821.

Lewy-MSA hybrid fold drives distinct neuronal α-synuclein pathology. Enomoto M, Martinez-Valbuena I et al. Commun Biol. 2025 Jun 16;8(1):929.

Small molecules restore mutant mitochondrial DNA polymerase activity. Valenzuela S, Zhu X et al. Nature. 2025 Jun 12;642(8067):501–507.

PLA2G15 is a BMP hydrolase and its targeting ameliorates lysosomal disease. Nyame K, Xiong J et al. Nature. 2025 Jun 12;642(8067):474–483.

Complex water networks visualized by cryogenic electron microscopy of RNA. Kretsch RC, Li S et al. Nature. 2025 Jun 5;642(8066):250–259.

More citations...

News

June 26, 2025

The ChimeraX 1.10 production release is available! See the change log for what's new.

May 7, 2025

The ChimeraX 1.10 release candidate is available – please try it and report any issues. See the change log for what's new.

March 19, 2025

Wiley most-cited-paper medallion
UCSF ChimeraX: Tools for structure building and analysis is one of the 10 most cited papers published in Protein Science in 2023!

Previous news...

Upcoming Events


UCSF ChimeraX

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see ChimeraX commercial licensing.

ChimeraX is developed with support from National Institutes of Health R01-GM129325.

Bluesky logo ChimeraX on Bluesky: @chimerax.ucsf.edu

Feature Highlight

multichannel 3D image of hiPSCs from AICS

Multichannel Light Microscopy

3D images and time series from multichannel optical microscopy are shown in the Volume Viewer tool, with easy access to hiding/showing individual channels, changing their colors, and adjusting threshold levels with the mouse. The menu of style options includes “volume” (translucent blobs, as in the image), surface, mesh, maximum intensity projection, single plane, and orthoplanes. For convenience, the step size, region bounds, and display style of different channels of the same dataset are coupled, in that changing the setting of one channel automatically changes it for the others.

The image shows human induced pluripotent stem cells, with plasma membrane in violet red, EGFP-tagged fibrillarin (as a marker for nucleolus) in yellow, and DNA (nucleus) in turquoise. The data are publicly available from the Allen Cell Explorer website, dataset: AICS-14_0.

More features...

Example Image

HIV-1 protease B-factor coloring

B-factor Coloring

Atomic B-factor values are read from PDB and mmCIF input files and assigned as attributes that can be shown with coloring and used in atom specification. This example shows B-factor variation within a structure of the HIV-1 protease bound to an inhibitor (PDB 4hvp). For complete image setup, including positioning, color key, and label, see the command file bfactor.cxc.

Additional color key examples can be found in tutorials: Coloring by Electrostatic Potential, Coloring by Sequence Conservation

More images...



About RBVI | Projects | People | Publications | Resources | Visit Us

Copyright 2018 Regents of the University of California. All rights reserved.