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ChimeraX Video Tutorials and Demonstrations

Videos showing how to use ChimeraX for various tasks. On other pages you can find tutorials with detailed written instructions and additional capabilities shown in web presentations and feature highlights and example images.

Electron Microscopy Maps

computer generated image SBGrid webinar: AlphaFold with predicted aligned error (PAE) plots for cryoEM modeling. March 29, 2022. computer generated image SBGrid webinar: AlphaFold for cryoEM modeling and its limitations. November 9, 2021.
computer generated image Run AlphaFold to compute a starting cryoEM atomic model. Looks at transporter of omega-3 fatty acids. September 6, 2021. computer generated image Fit an AlphaFold database model into a cryoEM map. September 6, 2021.
computer generated image Fit an atomic model into an electron microscopy map. Also use symmetry to build a full nanocage model. April 27, 2021. computer generated image Color an electron microscopy map by local resolution. April 14, 2021.
computer generated image Color each protein in an electron microscopy map. March 5, 2021. computer generated image Webinar intro to atomic models and X-ray and EM maps looking at SARS-CoV-2 nanobodies. Outline. March 25, 2021.
computer generated image Movie Making for cryoEM using ChimeraX SBGrid webinar. Written instructions. April 20, 2017. computer generated image Refining atomic models in cryoEM with ISOLDE SBGrid webinar presented by Tristan Croll. April 26, 2020.
computer generated image Rebuilding a cryo-EM model using ISOLDE by Tristan Croll. January 22, 2019.

Virtual Reality

computer generated image VR modeling of encapsulin and ferritin for the NIH Virtual and Augmented Reality Scientific Interest Group. Slides. February 17, 2022
computer generated image Tugging atoms in ISOLDE atomic refinement tool. March 22, 2021. computer generated image Making Augmented Reality Videos with ChimeraX SBGrid webinar. Slides. July 19, 2020.
computer generated image How coronaviruses get into cells presented with augmented reality. February 3, 2020. computer generated image Different kinds of opioids presented with augmented reality. November 20, 2019.
computer generated image Drug discovery with virtual reality Matt Jacobson and Beth Winger talk about use of VR to look at cancer drugs. October 16, 2019. computer generated image Medical imaging virtual reality tutorial. Detailed instructions. February 2019.

Atomic Structure Analysis

computer generated image Predict binding for batches of ligands with Boltz 2. August 20, 2025.
computer generated image Predict ligand binding affinity with Boltz 2. July 23, 2025. computer generated image Predict a transcription factor bound to DNA using Boltz. April 30, 2025.
computer generated image Color protein by C-alpha distances to an aligned protein. July 5, 2023. computer generated image Predict 3000 amino acid structures with AlphaFold. May 17, 2023.
computer generated image Color aligned proteins by C-alpha RMSD. February 14, 2023. computer generated image Fast AlphaFold predictions using ColabFold. July 17, 2022.
computer generated image Show AlphaFold binding error estimates. June 8, 2022. computer generated image Show AlphaFold error estimates. April 5, 2022.
computer generated image Show residues near a ligand. January 5, 2022. computer generated image Run AlphaFold to predict a complex. December 7, 2021.
computer generated image Compare AlphaFold structure prediction to an experimental structure of nitric oxide synthase. September 1, 2021. computer generated image Compute a protein structure from sequence using AlphaFold. Chicken avidin. September 1, 2021.
computer generated image Combine AlphaFold protein structures in an assembly and compare to an experimental human endonuclease complex. September 1, 2021. computer generated image Color by electrostatic potential nuclear export protein CRM1. April 21, 2021.

Exporting Models

Wave function display

computer generated image Export models from ChimeraX into Blender by Brady Johnston. February 28, 2021. computer generated image Plotting electron localization function (ELF) isosurface from Multiwfn. January 29, 2020.