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Featured Citations

Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery. Saurer M, Ramrath DJF et al. Science. 2019 Sep 13;365(6458):1144-1149.

CryoEM structures of Arabidopsis DDR complexes involved in RNA-directed DNA methylation. Wongpalee SP, Liu S et al. Nat Commun. 2019 Sep 2;10(1):3916.

Structure of the dynein-2 complex and its assembly with intraflagellar transport trains. Toropova K, Zalyte R et al. Nat Struct Mol Biol. 2019 Sep;26(9):823-829.

Conformational transitions of a neurotensin receptor 1-Gi1 complex. Kato HE, Zhang Y et al. Nature. 2019 Aug 1;572(7767):80-85.

A one-gate elevator mechanism for the human neutral amino acid transporter ASCT2. Garaeva AA, Guskov A et al. Nat Commun. 2019 Jul 31;10(1):3427.

See also: RCSB PDB Images
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News

June 20, 2019

ChimeraX virtual reality shown on PBS Newshour: How Close are Scientists to a Universal Flu Vaccine?

June 6, 2019

The ChimeraX 0.9 production release is available. See the change log for what's new.

May 30, 2019

From the Rochester Institute of Technology: Student develops tool to visualize molecular dynamics of proteins in virtual reality with ChimeraX.

Previous news...

Upcoming Events

September 24, 2019

At 12 pm EDT, Tristan Croll will give a live webinar on using ISOLDE, a ChimeraX plugin for interactively building high-quality atomic models into density maps of low-to-medium resolution. Later, the presentation will be posted on SBGridTV.


UCSF ChimeraX

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see licensing.

ChimeraX is developed with support from National Institutes of Health R01-GM129325 and the Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases.

Feature Highlight

4hhb ambient lighting

Ambient Occlusion Molecular Surfaces

Several lighting modes are available, including ambient occlusion. The image shows hemoglobin (PDB 4hhb) with the four chains shown as surfaces of different colors and heme residues as spheres. The command lighting soft or the Graphics icon can be used to turn on ambient shadowing from 64 directions. The command lighting gentle gives a similar result, except tuned to emphasize larger indentations.

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Example Image

photosynthetic reaction center

Photosynthetic Reaction Center

The photosynthetic reaction center from a purple sulfur bacterium is shown as a cartoon with “tube” helices and membrane boundaries from the OPM database (Orientations of Proteins in Membranes, entry 1eys). Blue and red balls represent the cytoplasmic and periplasmic sides of the bacterial inner membrane, respectively. The title and other text labels were added with the 2dlabels command and repositioned interactively with the move label mouse mode . ChimeraX session file: prc.cxs

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