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Featured Citations

Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis. Su T, Izawa T et al. Nature. 2019 Jun 27;570(7762):538-542.

Cryo-EM structure of Neurospora crassa respiratory complex IV. Bausewein T, Nussberger S, Kühlbrandt W. IUCrJ. 2019 Jun 26;6(Pt 4):773-780.

High-resolution cryo-EM structures of outbreak strain human norovirus shells reveal size variations. Jung J, Grant T et al. Proc Natl Acad Sci USA. 2019 Jun 25;116(26):12828-12832.

Rotary substates of mitochondrial ATP synthase reveal the basis of flexible F1-Fo coupling. Murphy BJ, Klusch N et al. Science. 2019 Jun 21;364(6446). pii: eaaw9128.

Conformational switches control early maturation of the eukaryotic small ribosomal subunit. Hunziker M, Barandun J et al. eLife. 2019 Jun 17;8. pii: e45185.

See also: RCSB PDB Images
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News

June 20, 2019

ChimeraX virtual reality shown on PBS Newshour: How Close are Scientists to a Universal Flu Vaccine?

June 6, 2019

The ChimeraX 0.9 production release is available. See the change log for what's new.

May 30, 2019

From the Rochester Institute of Technology: Student develops tool to visualize molecular dynamics of proteins in virtual reality with ChimeraX.

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UCSF ChimeraX

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see licensing.

ChimeraX is developed with support from National Institutes of Health R01-GM129325 and the Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases.

Feature Highlight

simple lighting soft lighting

cryoEM Ambient Occlusion

A cryoelectron microscopy map of the 26S proteasome (EMD-4321) is shown at the author-recommended contour level in two different lighting modes: “simple” on the left and “soft” on the right. Soft lighting includes ambient lighting and shadowing (occlusion) and can be turned on with the command lighting soft or by clicking the Graphics icon .

For setup of the righthand image, see the command file ambient.cxc.

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Example Image

photosynthetic reaction center

Photosynthetic Reaction Center

The photosynthetic reaction center from a purple sulfur bacterium is shown as a cartoon with “tube” helices and membrane boundaries from the OPM database (Orientations of Proteins in Membranes, entry 1eys). Blue and red balls represent the cytoplasmic and periplasmic sides of the bacterial inner membrane, respectively. The title and other text labels were added with the 2dlabels command and repositioned interactively with the move label mouse mode . ChimeraX session file: prc.cxs

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