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Featured Citations

Plug-in strategy for resistance engineering inspired by potato NLRome. Wang L, Li H et al. Nature. 2026 Jan 8;649(8096):396–405.

Deep contrastive learning enables genome-wide virtual screening. Jia Y, Gao B et al. Science. 2026 Jan 8;391(6781):eads9530.

Recurrent acquisition of nuclease-protease pairs in antiviral immunity. Tuck OT, Hu JJ et al. Science. 2026 Jan 8;391(6781):195-201.

Asynchronous subunit transitions prime acetylcholine receptor activation. Thompson MJ, Tessier CJG et al. Science. 2026 Jan 1;391(6780):eadw1264.

Mechanism of cotranslational modification of histones H2A and H4 by MetAP1 and NatD. Yudin D, Jaskolowski M et al. Sci Adv. 2025 Dec 19;11(51):eaeb1017.

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News

December 25, 2025

The RBVI wishes you a safe and happy holiday season! See our 2025 card and the gallery of previous cards back to 1985.

December 16, 2025

The ChimeraX 1.11 production release is available! See the change log for what's new.

November 21, 2025

The ChimeraX 1.11 release candidate is available – please try it and report any issues. See the change log for what's new. This will be the last release to support Red Hat Enterprise Linux 8 and its derivatives.

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UCSF ChimeraX

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see ChimeraX commercial licensing.

ChimeraX is developed with support from National Institutes of Health R01-GM129325.

Bluesky logo ChimeraX on Bluesky: @chimerax.ucsf.edu

Feature Highlight

Stylized Nucleotides

Different representations of nucleotides can be shown with the nucleotides command or Toolbar icons. Options include filled rings, slabs for bases (box, muffler, or ellipsoid shape), bumps on slabs to show base orientation, simple tubes instead of ribose atoms, and continuous or broken ladder rungs. Nucleotide representations can be the same color as the ribbon or a different color, and multiple nucleotide styles can be used within a single structure.

See also: Presets menu

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Example Image

photosynthetic reaction center

Photosynthetic Reaction Center

The photosynthetic reaction center from a purple sulfur bacterium is shown as a cartoon with “tube” helices and membrane boundaries from the OPM database (Orientations of Proteins in Membranes, entry 1eys). Blue and red balls represent the cytoplasmic and periplasmic sides of the bacterial inner membrane, respectively. The title and other text labels were added with the 2dlabels command and repositioned interactively with the move label mouse mode . ChimeraX session file: prc.cxs

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