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Featured Citations

Helicase-mediated mechanism of SSU processome maturation and disassembly. Buzovetsky O, Klinge S. Nature. 2025 Dec 18;648(8094):746–754.

A bacterial nutrition strategy for plant disease control. Wang S, Zhu L et al. Science. 2025 Dec 18;390(6779):1299-1304.

In situ structural mechanism of epothilone-B-induced CNS axon regeneration. Bodakuntla S, Taira K et al. Nature. 2025 Dec 11;648(8093):477–487.

Synthetic α-synuclein fibrils replicate in mice causing MSA-like pathology. Burger D, Kashyrina M et al. Nature. 2025 Dec 11;648(8093):409-417.

Multiscale structure of chromatin condensates explains phase separation and material properties. Zhou H, Huertas J et al. Science. 2025 Dec 4;390(6777):eadv6588.

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News

December 16, 2025

The ChimeraX 1.11 production release is available! See the change log for what's new.

November 21, 2025

The ChimeraX 1.11 release candidate is available – please try it and report any issues. See the change log for what's new. This will be the last release to support Red Hat Enterprise Linux 8 and its derivatives.

July 24, 2025

ChimeraX 1.10.1 is now available, fixing the problem in 1.10 of repeat registration requests to some users.

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UCSF ChimeraX

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see ChimeraX commercial licensing.

ChimeraX is developed with support from National Institutes of Health R01-GM129325.

Bluesky logo ChimeraX on Bluesky: @chimerax.ucsf.edu

Feature Highlight

Cartoon/Nucleotide Presets

The Presets menu includes a few different combinations of cartoon and nucleotide styles, shown here along with overall settings from the Publication preset plus lighting depthcue false. The style settings of cartoons and nucleotides can be controlled individually (and with many more possibilities than shown here) with cartoon style and nucleotides, respectively. See also: Toolbar nucleotides icons

6cmn ribbons/slabs 6cmn cylinders/stubs 6cmn licorice/ovals
ribbons/slabs cylinders/stubs licorice/ovals
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Example Image

cyclodextrin pore

Cyclodextrin Pore

The outer-membrane protein CymA admits bulky molecules into the periplasmic space of Klebsiella oxytoca. Here, CymA (PDB 4d5d chain A) is depicted in a style reminiscent of a diagnostic X-ray, with transparent molecular surface and β-strand “ribs” in white. The protein has ingested α-cyclodextrin (top) and β-cyclodextrin (bottom), bound at the entry site and near the exit, respectively. Cyclodextrin carbon atoms are shown in blue-gray and oxygen atoms in brick red. For image setup, see the command file xray.cxc.

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