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Glutamate gating of AMPA-subtype iGluRs at physiological temperatures. Kumar Mondal A, Carrillo E et al. Nature. 2025 May 15;641(8063):788–796.
Molecular basis of influenza ribonucleoprotein complex assembly and processive RNA synthesis. Peng R, Xu X et al. Science. 2025 May 15;388(6748):eadq7597.
High-resolution characterization of ex vivo AAT polymers by solution-state NMR spectroscopy. Lowen SM, Waudby CA et al. Sci Adv. 2025 May 9;11(19):eadu7064.
The RAD52 double-ring remodels replication forks restricting fork reversal. Honda M, Razzaghi M et al. Nature. 2025 May 8;641(8062):512–519.
Snapshots of acyl carrier protein shuttling in human fatty acid synthase. Schultz K, Costa-Pinheiro P et al. Nature. 2025 May 8;641(8062):520–528.
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May 7, 2025
The ChimeraX 1.10 release candidate is available – please try it and report any issues. See the change log for what's new.
March 19, 2025
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March 1, 2025
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UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. ChimeraX can be downloaded free of charge for academic, government, nonprofit, and personal use. Commercial users, please see ChimeraX commercial licensing.
ChimeraX is developed with support from National Institutes of Health R01-GM129325.
Feature Highlight
Anisotropic B-factor data can be shown as thermal ellipsoids, axes, or
ellipses with the
aniso command
or the Thermal
Ellipsoids tool. The image shows myoglobin structure
1jw8
with thermal ellipsoid representations of the heme residue and
protein sidechains that ligate or form H-bonds with the heme.
Metal coordination bonds are shown as purple dashed lines and H-bonds
as gold dashed lines.
Example Image
Influenza neuraminidase is an enzyme that promotes the spread of influenza
virus among host cells.
It is the target of oseltamivir and related antiviral drugs.
The image shows tetramers of neuraminidase (PDB
3k3a) styled as flowers. Three tetramers are in different
shades of pink, with a central metal ion in white and nearby residues in yellow,
and a fourth tetramer is colored green to resemble leaves.
Each monomer or “petal” is a six-bladed β-propeller.
For image setup other than orientation,
see the command file flowers.cxc.
The Chimera Image Gallery includes a similar image.
Thermal Ellipsoids
Neuraminidase Flowers
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