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Recent Citations

Hydrogen positions in single nanocrystals revealed by electron diffraction. Palatinus L, Brázda P et al. Science. 2017 Jan 13;355(6321):166-169.

Architecture of the yeast small subunit processome. Chaker-Margot M, Barandun J et al. Science. 2017 Jan 13;355(6321):aal1880.

Principles for designing proteins with cavities formed by curved β sheets. Marcos E, Basanta B et al. Science. 2017 Jan 13;355(6321):201-206.

Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome. Passos DO, Li M et al. Science. 2017 Jan 6;355(6320):89-92.

A supramolecular assembly mediates lentiviral DNA integration. Ballandras-Colas A, Maskell DP et al. Science. 2017 Jan 6;355(6320):93-95.

(Previously featured citations...)

Chimera Search

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News

December 2, 2016

Chimera production release 1.11.2 is now available. This version has been updated to work with changes in NCBI Blast and to avoid crashes on Mac Sierra (see the release notes for details).

September 24, 2016

Production release candidate (version 1.11.2) is available, superseding 1.11.1. The new version has been updated to work with changes in NCBI Blast (see release notes). Please try it and report any problems.

August 27, 2016

A production release candidate (version 1.11.1) is now available. Please try it and report any problems. See the release notes for what's been fixed since 1.11. The 1.11 release series will be the last to support 32-bit builds.

(Previous news...)

Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, nonprofit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), funded by the National Institutes of Health (NIGMS P41-GM103311).

UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera.

Feature Highlight

Nucleotides

Special representations of DNA and RNA can be displayed with the Nucleotides tool or the command nucleotides. Different levels of abstraction are available. The figure shows a ribbon backbone combined with the following sidechain (sugar/base) options:

  • ladder rungs
  • filled-ring atomic representations
  • "lollipops" in which bases are shown as ellipsoids and sugars as tubes
Bases can also be displayed as boxes or elliptical tubes, with or without bumps to indicate orientation. The colors of the special representations will update automatically to match the corresponding atoms.

(More features...)

Gallery Sample

Annotated Green Fluorescent Protein

BILD format was used in Chimera to annotate the barrel structure of green fluorescent protein with its centroid, major axis (red arrow), and an enclosing cylinder (shown with green hoops). The BILD file green.bild was generated with the python program green.py using the coordinates in green.pdb. Gallery entry courtesy of Mike Ess, Yeast Resource Center, University of Washington. (More samples...)