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Recent Citations

Biogenesis and structure of a type VI secretion membrane core complex. Durand E, Nguyen VS et al. Nature. 2015 Jul 30;523(7562):555-60.

Structural and biochemical characterization of AidC, a quorum-quenching lactonase with atypical selectivity. Mascarenhas R, Thomas PW et al. Biochemistry. 2015 Jul 21;54(28):4342-53.

A structure of the COPI coat and the role of coat proteins in membrane vesicle assembly. Dodonova SO, Diestelkoetter-Bachert P et al. Science. 2015 Jul 10;349(6244):195-198.

Cryo-EM structure of an antibody that neutralizes dengue virus type 2 by locking E protein dimers. Fibriansah G, Ibarra KD et al. Science. 2015 Jul 3;349(6243):88-91.

The architecture of the spliceosomal U4/U6.U5 tri-snRNP. Nguyen TH, Galej WP et al. Nature. 2015 Jul 2;523(7558):47-52.

(Previously featured citations...)

Chimera Search

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News

July 23, 2015

Chimera production release 1.10.2 is now available. Fixes include code signing for Mac OS X installation. The 1.10 series will be the last to support OS X 10.6 and 10.7. See the release notes for details.

January 9, 2015

Chimera production release 1.10.1 is now available. 64-bit builds are recommended for all capable platforms, and the 1.10 series will be the last to support OS X 10.6 and 10.7. See the release notes for details.

November 5, 2014

Chimera production release 1.10 is now available. 64-bit builds are recommended for all capable platforms, and v1.10 will be the last to support OS X 10.6 and 10.7. See the release notes for what's new.

(Previous news...)

Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics, funded by the National Institutes of Health (NIGMS P41-GM103311).

Feature Highlight

RR Distance Maps 2gbp and 2fw0

Distance Maps and Contact Maps

RR Distance Maps creates a distance map, a generalization of a protein contact map in which residue-residue distances are shown with color gradations. The map can show the Cα-Cα distances within an individual protein chain or the averages and standard deviations for multiple related chains (as in the figure). A simple binary coloring like a standard contact map can also be obtained.

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Gallery Sample

Peroxiredoxin Wreath

Peroxiredoxins are enzymes that help cells cope with stressors such as high levels of reactive oxygen species. The image shows a decameric peroxiredoxin from human red blood cells (Protein Data Bank entry 1qmv), styled as a holiday wreath. (More samples...)