Structure of the voltage-gated K+ channel Eag1 reveals an alternative voltage sensing mechanism. Whicher JR, MacKinnon R. Science. 2016 Aug 12;353(6300):664-9.
The acidic domain is a unique structural feature of the splicing factor SYNCRIP. Beuck C, Williamson JR et al. Protein Sci. 2016 Aug;25(8):1545-50.
HU multimerization shift controls nucleoid compaction. Hammel M, Amlanjyoti D et al. Sci Adv. 2016 Jul 29;2(7):e1600650.
Tetracarbalane structures: nido polyhedra and non-spherical deltahedra. Attia AA, Lupan A, King RB. Dalton Trans. 2016 Jul 28;45(28):11528-39.
Helical arrays of U-shaped ATP synthase dimers form tubular cristae in ciliate mitochondria. Mühleip AW, Joos F et al. Proc Natl Acad Sci USA. 2016 Jul 26;113(30):8442-7.(Previously featured citations...)
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August 26, 2016
A production release candidate (version 1.11.1) is now available. Please try it and report any problems. See the release notes for what's been fixed since 1.11. The 1.11 release series will be the last to support 32-bit builds.
July 15, 2016
June 23, 2016
PLOS Computational Biology announces winning T-shirt design created by Luigi Di Costanzo (RCSB Protein Data Bank) using UCSF Chimera.(Previous news...)
UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics (RBVI), funded by the National Institutes of Health (NIGMS P41-GM103311).
UCSF ChimeraX (or simply ChimeraX) is the next-generation molecular visualization program from the RBVI, following UCSF Chimera. It is in early development and not yet publicly released, with release anticipated sometime in 2016.
A structure can be colored to show values of an attribute such as atomic B-factor. The image includes a molecular surface that has been clipped and capped, 2D labels, and a color key. Color Zone was used to color the planar cross-section of the surface (see image how-to).(More features...)
Thermosomes are hollow balls inside which proteins are folded. They are found in the cytosol of eukaryotes and in archaea. Eukaryotic thermosomes have 8 different protein subunits, while archaeal ones are composed of one, two or three different proteins. The one shown from Thermoplasma acidophilum has two distinct proteins colored blue and yellow, each present in 8 copies. The two proteins have 60% sequence identity and are very similar in structure. One monomer is shown as a ribbon. Actin and tubulin are folded by eukaryotic thermosomes.
Protein Data Bank model 1a6d.(More samples...)