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Mechanism of Tc toxin action revealed in molecular detail. Meusch D, Gatsogiannis C et al. Nature. 2014 Apr 3;508(7494):61-5.

Structural basis for pure antagonism of integrin αVβ3 by a high-affinity form of fibronectin. Van Agthoven JF, Xiong JP et al. Nat Struct Mol Biol. 2014 Apr;21(4):383-8.

A mass spectrometry-based hybrid method for structural modeling of protein complexes. Politis A, Stengel F et al. Nat Methods. 2014 Apr;11(4):403-6.

Structure of the yeast mitochondrial large ribosomal subunit. Amunts A, Brown A et al. Science. 2014 Mar 28;343(6178):1485-9.

Patches of disorganization in the neocortex of children with autism. Stoner R, Chow ML et al. N Engl J Med. 2014 Mar 27;370(13):1209-19.

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Chimera Search

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News

October 31, 2013

Chimera production release 1.8.1 is now available. Changes since 1.8 are mainly to fix problems with Mac OS X 10.9 (Mavericks). See the release notes for further details and for a list of new features since the 1.7 release.

June 7, 2013

Chimera production release 1.8 is now available. See the release notes for new features since the 1.7 release.

April 18, 2013

A production release candidate (version 1.8) is now available; please try it and report any problems. See the release notes for changes relative to the previous release.

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Upcoming Events

UCSF Chimera is a highly extensible program for interactive visualization and analysis of molecular structures and related data, including density maps, supramolecular assemblies, sequence alignments, docking results, trajectories, and conformational ensembles. High-quality images and animations can be generated. Chimera includes complete documentation and several tutorials, and can be downloaded free of charge for academic, government, non-profit, and personal use. Chimera is developed by the Resource for Biocomputing, Visualization, and Informatics, funded by the National Institutes of Health (NIGMS P41-GM103311).

Feature Highlight

hydrogen bonds

Chemical Knowledge

  • determination of atom types in arbitrary molecules, including non-standard residues
  • ability to add hydrogen atoms
  • high-quality hydrogen bond identification
  • selection of atoms/bonds by element, atom type, functional group, amino acid category
  • interactive bond rotation, distance and angle measurements

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Gallery Sample

Clathrin

This image of a clathrin cage uses flat shading and edge highlighting. It is a copy of a PDB molecule of the month image made by Graham Johnson and Dave Goodsell. David Goodsell pioneered this visualization style. This image was made with the Multiscale tool, silhouette edging, and surface lighting turned off.

Protein Data Bank model 1xi4.

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