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A molecular network of conserved factors keeps ribosomes dormant in the egg. Leesch F, Lorenzo-Orts L et al. Nature. 2023 Jan 26;613(7945):712-720.

Structural basis for intrinsic transcription termination. You L, Omollo EO et al. Nature. 2023 Jan 26;613(7945):783-789.

Structural basis of broad-spectrum β-lactam resistance in Staphylococcus aureus. Alexander JAN, Worrall LJ et al. Nature. 2023 Jan 12;613(7943):375–382.

Structure of a volume-regulated heteromeric LRRC8A/C channel. Rutz S, Deneka D et al. Nat Struct Mol Biol. 2023 Jan;30(1):52-61.

Alignment of major-groove hydrogen bond arrays uncovers shared information between different DNA sequences that bind the same protein. Sedhom J, Kinser J, Solomon LA. NAR Genom Bioinform. 2022 Dec 31;4(4):lqac101.

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December 21, 2022

The RBVI wishes you a safe and happy holiday season! See our 2022 card and the gallery of previous cards back to 1985.

September 27, 2022

Website downtime: The RBVI website (Chimera, ChimeraX, etc.) and RBVI-hosted web services will be down for maintenance from Tue, Sep 27 9pm PDT, through Wed, possibly extending to Thu, Sep 29 5pm PDT.

December 20, 2021

The RBVI wishes you a safe and happy holiday season! See our 2021 card and the gallery of previous cards back to 1985.

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Please note that UCSF Chimera is legacy software that is no longer being developed or supported. Users are strongly encouraged to try UCSF ChimeraX, which is under active development.

UCSF Chimera is a program for the interactive visualization and analysis of molecular structures and related data, including density maps, trajectories, and sequence alignments. It is available free of charge for noncommercial use. Commercial users, please see Chimera commercial licensing.

We encourage Chimera users to try ChimeraX for much better performance with large structures, as well as other major advantages and completely new features. ChimeraX includes a significant subset of Chimera features (with more to come, see the missing features list) and is under active development. Users may choose to use both programs, and it is fine to have both installed.

Chimera is no longer under active development. Chimera development was supported by a grant from the National Institutes of Health (P41-GM103311) that ended in 2018.

Feature Highlight

ambient-only lighting

Simple Line Drawing

A simple, line-drawing-like appearance can be achieved by combining black silhouette edges with flat, ambient-only lighting. The image at left of a small molecule in ball-and-stick style can be generated with a few Chimera commands. The same visual effects can be applied to ribbons and other representations, as shown in Neuraminidase Flowers and other Image Gallery entries.

(More features...)

Gallery Sample

Molecular Bracelet

Eukaryotic initiation factor (eIF) complex (from Protein Data Bank entry 1rf8) in which eIF4E, shown with blue ribbons, is completely encircled by eIF4G, shown with yellow ribbons and red molecular surface (image creation details). (More samples...)


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