home overview research resources outreach & training outreach & training visitors center visitors center search search

Quick Links

Chimera Search

Google™ Search

Citations (partial list)

Structure of a prehandover mammalian ribosomal SRP·SRP receptor targeting complex. Kobayashi K, Jomaa A et al. Science. 2018 Apr 20;360(6386):323-327.

Structure of the herpes simplex virus 1 capsid with associated tegument protein complexes. Dai X, Zhou ZH. Science. 2018 Apr 6;360(6384). pii: eaao7298.

Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis. Scapin G, Dandey VP et al. Nature. 2018 Apr 5;556(7699):122-125.

Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule. Tsai JC, Miller-Vedam LE et al. Science. 2018 Mar 30;359(6383).

Binding of ISRIB reveals a regulatory site in the nucleotide exchange factor eIF2B. Zyryanova AF, Weis F et al. Science. 2018 Mar 30;359(6383):1533-1536.

EF-Tu and EF-G are activated by allosteric effects. Mondal D, Warshel A. Proc Natl Acad Sci USA. 2018 Mar 27;115(13):3386-3391.

Ligand binding site structure influences the evolution of protein complex function and topology. Abrusán G, Marsh JA. Cell Rep. 2018 Mar 20;22(12):3265-3276.

Lipids shape the electron acceptor-binding site of the peripheral membrane protein dihydroorotate dehydrogenase. Costeira-Paulo J, Gault J et al. Cell Chem Biol. 2018 Mar 15;25(3):309-317.e4.

The 3.5-Å cryoEM structure of nanodisc-reconstituted yeast vacuolar ATPase Vo proton channel. Roh SH, Stam NJ et al. Mol Cell. 2018 Mar 15;69(6):993-1004.e3.

Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility. Grotjahn DA, Chowdhury S et al. Nat Struct Mol Biol. 2018 Mar;25(3):203-207.

The cryo-electron microscopy structure of huntingtin. Guo Q, Bin Huang et al. Nature. 2018 Mar 1;555(7694):117-120.

Structural prediction of protein models using distance restraints derived from cross-linking mass spectrometry data. Orbán-Németh Z, Beveridge R et al. Nat Protoc. 2018 Mar;13(3):478-494.

A recurrent kinase domain mutation in PRKCA defines chordoid glioma of the third ventricle. Goode B, Mondal G et al. Nat Commun. 2018 Feb 23;9(1):810.

Electron cryo-microscopy structure of Ebola virus nucleoprotein reveals a mechanism for nucleocapsid-like assembly. Su Z, Wu C et al. Cell. 2018 Feb 22;172(5):966-978.e12.

A structural model of a p450-ferredoxin complex from orientation-selective double electron-electron resonance spectroscopy. Bowen AM, Johnson EOD et al. J Am Chem Soc. 2018 Feb 21;140(7):2514-2527.

3.3-Å resolution cryo-EM structure of human ribonucleotide reductase with substrate and allosteric regulators bound. Brignole EJ, Tsai KL et al. eLife. 2018 Feb 20;7. pii: e31502.

A global view of structure-function relationships in the tautomerase superfamily. Davidson R, Baas BJ et al. J Biol Chem. 2018 Feb 16;293(7):2342-2357.

Cryo-EM reconstruction of Type VI secretion system baseplate and sheath distal end. Nazarov S, Schneider JP et al. EMBO J. 2018 Feb 15;37(4). pii: e97103.

Cryo-EM shows how dynactin recruits two dyneins for faster movement. Urnavicius L, Lau CK et al. Nature. 2018 Feb 7;554(7691):202-206.

Structural insights into the mechanisms of CNBD channel function. James ZM, Zagotta WN. J Gen Physiol. 2018 Feb 5;150(2):225-244.

Structure of the yeast oligosaccharyltransferase complex gives insight into eukaryotic N-glycosylation. Wild R, Kowal J et al. Science. 2018 Feb 2;359(6375):545-550.

Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes. Poepsel S, Kasinath V, Nogales E. Nat Struct Mol Biol. 2018 Feb;25(2):154-162.

Structure and mutagenesis reveal essential capsid protein interactions for KSHV replication. Dai X, Gong D et al. Nature. 2018 Jan 25;553(7689):521-525.

A systematic analysis of nucleosome core particle and nucleosome-nucleosome stacking structure. Korolev N, Lyubartsev AP, Nordenskiöld L. Sci Rep. 2018 Jan 24;8(1):1543.

A self-assembled nanoscale robotic arm controlled by electric fields. Kopperger E, List J et al. Science. 2018 Jan 19;359(6373):296-301.

Multiplexed gene synthesis in emulsions for exploring protein functional landscapes. Plesa C, Sidore AM et al. Science. 2018 Jan 19;359(6373):343-347.

Dicer uses distinct modules for recognizing dsRNA termini. Sinha NK, Iwasa J et al. Science. 2018 Jan 19;359(6373):329-334.

Structure of the human TRPM4 ion channel in a lipid nanodisc. Autzen HE, Myasnikov AG et al. Science. 2018 Jan 12;359(6372). pii: eaar4510.

Cryo EM structure of intact rotary H+-ATPase/synthase from Thermus thermophilus. Nakanishi A, Kishikawa JI et al. Nat Commun. 2018 Jan 8;9(1):89.

Site-specific disulfide crosslinked nucleosomes with enhanced stability. Frouws TD, Barth PD, Richmond TJ. J Mol Biol. 2018 Jan 5;430(1):45-57.

Development of a genetically encodable FRET system using fluorescent RNA aptamers. Jepsen MDE, Sparvath SM et al. Nat Commun. 2018 Jan 2;9(1):18.

Integrative structure modeling with the Integrative Modeling Platform. Webb B, Viswanath S et al. Protein Sci. 2018 Jan;27(1):245-258.

Cryo-EM structure of the bifunctional secretin complex of Thermus thermophilus. D'Imprima E, Salzer R et al. eLife. 2017 Dec 27;6. pii: e30483.

Proteasomes tether to two distinct sites at the nuclear pore complex. Albert S, Schaffer M et al. Proc Natl Acad Sci USA. 2017 Dec 26;114(52):13726-13731.

Structural studies of Chikungunya virus maturation. Yap ML, Klose T et al. Proc Natl Acad Sci USA. 2017 Dec 26;114(52):13703-13707.

Acquisition of functions on the outer capsid surface during evolution of double-stranded RNA fungal viruses. Mata CP, Luque D et al. PLoS Pathog. 2017 Dec 8;13(12):e1006755.

Structure of the yeast spliceosomal postcatalytic P complex. Liu S, Li X et al. Science. 2017 Dec 8;358(6368):1278-1283.

Allosteric nanobodies uncover a role of hippocampal mGlu2 receptor homodimers in contextual fear consolidation. Scholler P, Nevoltris D et al. Nat Commun. 2017 Dec 6;8(1):1967.

Atomic structures of minor proteins VI and VII in the human adenovirus. Dai X, Wu L et al. J Virol. 2017 Dec;91(24):00850-17.

Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras. Xu S, Long BN et al. Acta Crystallogr D Struct Biol. 2017 Dec 1;73(Pt 12):970-984.

3.9 Å structure of the yeast Mec1-Ddc2 complex, a homolog of human ATR-ATRIP. Wang X, Ran T et al. Science. 2017 Dec 1;358(6367):1206-1209.

Structural basis for the initiation of eukaryotic transcription-coupled DNA repair. Xu J, Lahiri I et al. Nature. 2017 Nov 30;551(7682):653-657.

Primer synthesis by a eukaryotic-like archaeal primase is independent of its Fe-S cluster. Holzer S, Yan J et al. Nat Commun. 2017 Nov 23;8(1):1718.

Atomic model for the dimeric FO region of mitochondrial ATP synthase. Guo H, Bueler SA, Rubinstein JL. Science. 2017 Nov 17;358(6365):936-940.

Structural basis of bacterial transcription activation. Liu B, Hong C et al. Science. 2017 Nov 17;358(6365):947-951.

Structure and assembly of the Ebola virus nucleocapsid. Wan W, Kolesnikova L et al. Nature. 2017 Nov 16;551(7680):394-397.

Customizable de novo design strategies for DOCK: Application to HIVgp41 and other therapeutic targets. Allen WJ, Fochtman BC et al. J Comput Chem. 2017 Nov 15;38(30):2641-2663.

Structural insight into TPX2-stimulated microtubule assembly. Zhang R, Roostalu J et al. eLife. 2017 Nov 9;6. pii: e30959.

Structures of transcription pre-initiation complex with TFIIH and Mediator. Schilbach S, Hantsche M et al. Nature. 2017 Nov 9;551(7679):204-209.

Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing. Puchades C, Rampello AJ et al. Science. 2017 Nov 3;358(6363). pii: eaao0464.

Design of coiled-coil protein-origami cages that self-assemble in vitro and in vivo. Ljubetič A, Lapenta F et al. Nat Biotechnol. 2017 Nov;35(11):1094-1101.

Solvatochromism and preferential solvation of Brooker's merocyanine in water-methanol mixtures. Tanaka Y, Kawashima Y et al. J Comput Chem. 2017 Oct 30;38(28):2411-2419.

CryoEM structure of Saccharomyces cerevisiae U1 snRNP offers insight into alternative splicing. Li X, Liu S et al. Nat Commun. 2017 Oct 19;8(1):1035.

Capsids and genomes of jumbo-sized bacteriophages reveal the evolutionary reach of the HK97 fold. Hua J, Huet A et al. MBio. 2017 Oct 17;8(5). pii: e01579-17.

Competing scaffolding proteins determine capsid size during mobilization of Staphylococcus aureus pathogenicity islands. Dearborn AD, Wall EA et al. eLife. 2017 Oct 6;6. pii: e30822.

Conformational entropy as collective variable for proteins. Palazzesi F, Valsson O, Parrinello M. J Phys Chem Lett. 2017 Oct 5;8(19):4752-4756

Cryo-EM Structures Reveal Mechanism and Inhibition of DNA Targeting by a CRISPR-Cas Surveillance Complex. Guo TW, Bartesaghi A et al. Cell. 2017 Oct 5;171(2):414-426.e12.

Structure of the human mitochondrial ribosome studied in situ by cryoelectron tomography. Englmeier R, Pfeffer S, Förster F. Structure. 2017 Oct 3;25(10):1574-1581.e2.

A PDZ-like domain mediates the dimerization of 11R-lipoxygenase. Eek P, Põldemaa K et al. Biochim Biophys Acta. 2017 Oct;1862(10 Pt A):1121-1128.

The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus. Matzov D, Aibara S et al. Nat Commun. 2017 Sep 28;8(1):723.

Actin-based protrusions of migrating neutrophils are intrinsically lamellar and facilitate direction changes. Fritz-Laylin LK, Riel-Mehan M et al. eLife. 2017 Sep 26;6. pii: e26990.

GaudiMM: A modular multi-objective platform for molecular modeling. Rodríguez-Guerra Pedregal J, Sciortino G et al. J Comput Chem. 2017 Sep 15;38(24):2118-2126.

Structural basis of MsbA-mediated lipopolysaccharide transport. Mi W, Li Y et al. Nature. 2017 Sep 14;549(7671):233-237.

Lis1 has two opposing modes of regulating cytoplasmic dynein. DeSantis ME, Cianfrocco MA et al. Cell. 2017 Sep 7;170(6):1197-1208.e12.

Refined cryo-EM structure of the T4 tail tube: Exploring the lowest dose limit. Zheng W, Wang F et al. Structure. 2017 Sep 5;25(9):1436-1441.e2.

Structures of Medicago truncatula L-histidinol dehydrogenase show rearrangements required for NAD+ binding and the cofactor positioned to accept a hydride. Ruszkowski M, Dauter Z. Sci Rep. 2017 Sep 5;7(1):10476.

Differential replication of foot-and-mouth disease viruses in mice determine lethality. Cacciabue M, García-Núñez MS et al. Virology. 2017 Sep;509:195-204.

Katanin spiral and ring structures shed light on power stroke for microtubule severing. Zehr E, Szyk A et al. Nat Struct Mol Biol. 2017 Sep;24(9):717-725.

ISWI chromatin remodellers sense nucleosome modifications to determine substrate preference. Dann GP, Liszczak GP et al. Nature. 2017 Aug 31;548(7669):607-611.

Morphologies of synaptic protein membrane fusion interfaces. Gipson P, Fukuda Y et al. Proc Natl Acad Sci USA. 2017 Aug 22;114(34):9110-9115.

Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE. Fellner M, Desguin B et al. Proc Natl Acad Sci USA. 2017 Aug 22;114(34):9074-9079.

A cyclic oligonucleotide signaling pathway in type III CRISPR-Cas systems. Kazlauskiene M, Kostiuk G et al. Science. 2017 Aug 11;357(6351):605-609.

Proteins evolve on the edge of supramolecular self-assembly. Garcia-Seisdedos H, Empereur-Mot C et al. Nature. 2017 Aug 10;548(7666):244-247.

Enriching traditional protein-protein interaction networks with alternative conformations of proteins. Halakou F, Kilic ES et al. Sci Rep. 2017 Aug 3;7(1):7180.

Cryo-EM structure of the SAGA and NuA4 coactivator subunit Tra1 at 3.7 angstrom resolution. Díaz-Santín LM, Lukoyanova N et al. eLife. 2017 Aug 2;6. pii: e28384.

Crystal structure and functional analysis of Leishmania major pseudoperoxidase. Chreifi G, Dejam D, Poulos TL. J Biol Inorg Chem. 2017 Aug;22(6):919-927.

RosettaES: a sampling strategy enabling automated interpretation of difficult cryo-EM maps. Frenz B, Walls AC et al. Nat Methods. 2017 Aug;14(8):797-800.

ChromEMT: Visualizing 3D chromatin structure and compaction in interphase and mitotic cells. Ou HD, Phan S et al. Science. 2017 Jul 28;357(6349):eaag0025.

Capturing protein communities by structural proteomics in a thermophilic eukaryote. Kastritis PL, O'Reilly FJ et al. Mol Syst Biol. 2017 Jul 25;13(7):936.

Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104. Gates SN, Yokom AL et al. Science. 2017 Jul 21;357(6348):273-279.

Automatic analysis and 3D-modelling of Hi-C data using TADbit reveals structural features of the fly chromatin colors. Serra F, Baù D et al. PLoS Comput Biol. 2017 Jul 19;13(7):e1005665.

Using molecular visualization to explore protein structure and function and enhance student facility with computational tools. Terrell CR, Listenberger LL. Biochem Mol Biol Educ. 2017 Jul 8;45(4):318-328.

Recognition of EGF-like domains by the Notch-modifying O-fucosyltransferase POFUT1. Li Z, Han K et al. Nat Chem Biol. 2017 Jul;13(7):757-763.

Dual host specificity of phage SP6 is facilitated by tailspike rotation. Tu J, Park T et al. Virology. 2017 Jul;507:206-215.

Improved metrics for comparing structures of macromolecular assemblies determined by 3D electron-microscopy. Joseph AP, Lagerstedt I et al. J Struct Biol. 2017 Jul;199(1):12-26.

Atomic structure of the human cytomegalovirus capsid with its securing tegument layer of pp150. Yu X, Jih J et al. Science. 2017 Jun 30;356(6345):eaam6892.

Structure and conformational dynamics of scaffolded DNA origami nanoparticles. Pan K, Bricker WP et al. Nucleic Acids Res. 2017 Jun 20;45(11):6284-6298.

Structural mechanism of ATP-independent transcription initiation by RNA polymerase I. Han Y, Yan C et al. eLife. 2017 Jun 17;6. pii: e27414.

Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes. Alamo L, Ware JS et al. eLife. 2017 Jun 13;6. pii: e24634.

Cryo-EM structure of the activated GLP-1 receptor in complex with a G protein. Zhang Y, Sun B et al. Nature. 2017 Jun 8;546(7657):248-253.

The CaMKII holoenzyme structure in activation-competent conformations. Myers JB, Zaegel V et al. Nat Commun. 2017 Jun 7;8:15742.

Structural basis for antibody-mediated neutralization of Lassa virus. Hastie KM, Zandonatti MA et al. Science. 2017 Jun 2;356(6341):923-928.

Cryo-electron microscopy of chromatin biology. Wilson MD, Costa A. Acta Crystallogr D Struct Biol. 2017 Jun 1;73(Pt 6):541-548.

Halogenated ether, alcohol, and alkane anesthetics activate TASK-3 tandem pore potassium channels likely through a common mechanism. Luethy A, Boghosian JD et al. Mol Pharmacol. 2017 Jun;91(6):620-629.

Phase-plate cryo-EM structure of a class B GPCR-G-protein complex. Liang YL, Khoshouei M et al. Nature. 2017 Jun 1;546(7656):118-123.

Large-scale analysis of hydrogen bond interaction patterns in protein-ligand interfaces. Nittinger E, Inhester T et al. J Med Chem. 2017 May 25;60(10):4245-4257.

ArbAlign: A tool for optimal alignment of arbitrarily ordered isomers using the Kuhn-Munkres algorithm. Temelso B, Mabey JM et al. J Chem Inf Model. 2017 May 22;57(5):1045-1054.

Cryo-EM structure of human adenovirus D26 reveals the conservation of structural organization among human adenoviruses. Yu X, Veesler D et al. Sci Adv. 2017 May 10;3(5):e1602670.

Relation between molecular electronic structure and nuclear spin-induced circular dichroism. Štěpánek P, Coriani S et al. Sci Rep. 2017 Apr 24;7:46617.

Architecture of a transcribing-translating expressome. Kohler R, Mooney RA et al. Science. 2017 Apr 14;356(6334):194-197.