
Citations (partial list)
Structural basis for inactivation of PRC2 by G-quadruplex RNA. Song J, Gooding AR et al. Science. 2023 Sep 22;381(6664):1331-1337.
Structural basis of mitochondrial protein import by the TIM23 complex. Sim SI, Chen Y et al. Nature. 2023 Sep 21;621(7979):620–626.
Neutralization, effector function and immune imprinting of Omicron variants. Addetia A, Piccoli L et al. Nature. 2023 Sep 21;621(7979):592–601.
A pentameric TRPV3 channel with a dilated pore. Lansky S, Betancourt JM et al. Nature. 2023 Sep 7;621(7977):206–214.
DELE1 oligomerization promotes integrated stress response activation. Yang J, Baron KR et al. Nat Struct Mol Biol. 2023 Sep;30(9):1295-1302.
OPA1 helical structures give perspective to mitochondrial dysfunction. Nyenhuis SB, Wu X et al. Nature. 2023 Aug 31;620(7976):1109–1116.
Computation of absolute binding free energies for noncovalent inhibitors with SARS-CoV-2 main protease. Ghahremanpour MM, Saar A et al. J Chem Inf Model. 2023 Aug 28;63(16):5309-5318.
Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1. Liu CP, Yu Z et al. Science. 2023 Aug 25;381(6660):eadd8673.
Cryo-EM structure of the nucleocapsid-like assembly of respiratory syncytial virus. Wang Y, Zhang C et al. Signal Transduct Target Ther. 2023 Aug 22;8(1):323.
Diverse modes of H3K36me3-guided nucleosomal deacetylation by Rpd3S. Guan H, Wang P et al. Nature. 2023 Aug 17;620(7974):669-675.
Structural basis for the binding of DNP and purine nucleotides onto UCP1. Kang Y, Chen L. Nature. 2023 Aug 3;620(7972):226–231.
Investigation of hydrated channels and proton pathways in a high-resolution cryo-EM structure of mammalian complex I. Grba DN, Chung I et al. Sci Adv. 2023 Aug 2;9(31):eadi1359.
Electrostatic ratchet for successive peptide synthesis in nonribosomal molecular machine RimK. Ohnuki J, Arimura Y et al. J Am Chem Soc. 2023 Jul 26;145(29):15963-15970.
Structures of 9-1-1 DNA checkpoint clamp loading at gaps from start to finish and ramification on biology. Zheng F, Georgescu RE et al. Cell Rep. 2023 Jul 25;42(7):112694.
Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Li M, Oliveira Passos D et al. Sci Adv. 2023 Jul 21;9(29):eadg5953.
Histone modifications regulate pioneer transcription factor cooperativity. Sinha KK, Bilokapic S et al. Nature. 2023 Jul 13;619(7969):378–384.
Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens. Martin GM, Russell RA et al. NPJ Vaccines. 2023 Jul 13;8(1):101.
Organic-inorganic covalent-ionic molecules for elastic ceramic plastic. Fang W, Mu Z et al. Nature. 2023 Jul 13;619(7969):293–299.
Residue-level error detection in cryoelectron microscopy models. Reggiano G, Lugmayr W et al. Structure. 2023 Jul 6;31(7):860-869.e4.
A multi-enzyme machine polymerizes the Haemophilus influenzae type b capsule. Cifuente JO, Schulze J et al. Nat Chem Biol. 2023 Jul;19(7):865-877.
Structural basis for FGF hormone signalling. Chen L, Fu L et al. Nature. 2023 Jun 22;618(7966):862–870.
Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes. White JBR, Silale A et al. Nature. 2023 Jun 15;618(7965):583–589.
Structural model for factor X inhibition of IgM and complement-mediated neutralization of adenovirus. Wagner N, Shayakhmetov DM, Stewart PL. Viruses. 2023 Jun 9;15(6):1343.
Nuclear export of pre-60S particles through the nuclear pore complex. Li Z, Chen S et al. Nature. 2023 Jun 8;618(7964):411–418.
Structural basis of amine odorant perception by a mammal olfactory receptor. Guo L, Cheng J et al. Nature. 2023 Jun 1;618(7963):193–200.
Ligand and G-protein selectivity in the κ-opioid receptor. Han J, Zhang J et al. Nature. 2023 May 11;617(7960):417-425.
Redox potentials of uranyl ions in macrocyclic complexes: Quantifying the role of counter-ions. Sundararajan M. ACS Omega. 2023 May 10;8(20):18041-18046.
MELD-Bracket ranks binding affinities of diverse sets of ligands. Parui S, Robertson JC et al. J Chem Inf Model. 2023 May 8;63(9):2857-2865.
Molecular basis of translation termination at noncanonical stop codons in human mitochondria. Saurer M, Leibundgut M et al. Science. 2023 May 5;380(6644):531-536.
Structural basis of BAM-mediated outer membrane β-barrel protein assembly. Shen C, Chang S et al. Nature. 2023 May 4;617(7959):85–193.
Lesion recognition by XPC, TFIIH and XPA in DNA excision repair. Kim J, Li CL et al. Nature. 2023 May 4;617(7959):170–175.
A structural basis for prion strain diversity. Manka SW, Wenborn A et al. Nat Chem Biol. 2023 May;19(5):607-613.
Csx28 is a membrane pore that enhances CRISPR-Cas13b-dependent antiphage defense. VanderWal AR, Park JU et al. Science. 2023 Apr 28;380(6643):410-415.
Structural basis for GSDMB pore formation and its targeting by IpaH7.8. Wang C, Shivcharan S et al. Nature. 2023 Apr 20;616(7957):590–597.
Structural basis of sensory receptor evolution in octopus. Allard CAH, Kang G et al. Nature. 2023 Apr 13;616(7956):373-377.
Germline-encoded amino acid-binding motifs drive immunodominant public antibody responses. Shrock EL, Timms RT et al. Science. 2023 Apr 7;380(6640):eadc9498.
Unsaturated bond recognition leads to biased signal in a fatty acid receptor. Mao C, Xiao P et al. Science. 2023 Apr 7;380(6640):eadd6220.
Norovirus MLKL-like protein initiates cell death to induce viral egress. Wang G, Zhang D et al. Nature. 2023 Apr 6;616(7955):152–158.
Structural and mechanistic insights into fungal β-1,3-glucan synthase FKS1. Hu X, Yang P et al. Nature. 2023 Apr 6;616(7955):190–198.
A sequence-based foldability score combined with AlphaFold2 predictions to disentangle the protein order/disorder continuum. Bruley A, Bitard-Feildel T et al. Proteins. 2023 Apr;91(4):466-484.
Integrative structural analysis of the type III secretion system needle complex from Shigella flexneri. Flacht L, Lunelli M et al. Protein Sci. 2023 Apr;32(4):e4595.
Immunoglobulin M perception by FcμR. Li Y, Shen H et al. Nature. 2023 Mar 30;615(7954):907–912.
Cysteine carboxyethylation generates neoantigens to induce HLA-restricted autoimmunity. Zhai Y, Chen L et al. Science. 2023 Mar 17;379(6637):eabg2482.
Structure of the human DICER-pre-miRNA complex in a dicing state. Lee YY, Lee H et al. Nature. 2023 Mar 9;615(7951):331–338.
Structure and function of Plasmodium actin II in the parasite mosquito stages. Lopez AJ, Andreadaki M et al. PLoS Pathog. 2023 Mar 6;19(3):e1011174.
Variable microtubule architecture in the malaria parasite. Ferreira JL, Pražák V et al. Nat Commun. 2023 Mar 3;14(1):1216.
Human PRPS1 filaments stabilize allosteric sites to regulate activity. Hvorecny KL, Hargett K et al. Nat Struct Mol Biol. 2023 Mar;30(3):391-402.
In situ cryo-electron tomography reveals the asymmetric architecture of mammalian sperm axonemes. Chen Z, Greenan GA et al. Nat Struct Mol Biol. 2023 Mar;30(3):360-369.
How to compile different types of structural visualizations in one panel. Bu F, Kompaniiets D, Liu B. Trends Biochem Sci. 2023 Mar;48(3):303-304.
Structural basis for substrate selection by the SARS-CoV-2 replicase. Malone BF, Perry JK et al. Nature. 2023 Feb 23;614(7949):781–787.
Menin “reads” H3K79me2 mark in a nucleosomal context. Lin J, Wu Y et al. Science. 2023 Feb 17;379(6633):717-723.
Structural basis of Rho-dependent transcription termination. Molodtsov V, Wang C et al. Nature. 2023 Feb 9;614(7947):367–374.
Structural basis of V-ATPase VO region assembly by Vma12p, 21p, and 22p. Wang H, Bueler SA, Rubinstein JL. Proc Natl Acad Sci USA. 2023 Feb 7;120(6):e2217181120.
Principles of mitoribosomal small subunit assembly in eukaryotes. Harper NJ, Burnside C, Klinge S. Nature. 2023 Feb 2;614(7946):175–181.
Human DNA-dependent protein kinase activation mechanism. Liang S, Blundell TL. Nat Struct Mol Biol. 2023 Feb;30(2):140-147.
A molecular network of conserved factors keeps ribosomes dormant in the egg. Leesch F, Lorenzo-Orts L et al. Nature. 2023 Jan 26;613(7945):712-720.
Structural basis for intrinsic transcription termination. You L, Omollo EO et al. Nature. 2023 Jan 26;613(7945):783-789.
Structural basis of broad-spectrum β-lactam resistance in Staphylococcus aureus. Alexander JAN, Worrall LJ et al. Nature. 2023 Jan 12;613(7943):375–382.
Structure of a volume-regulated heteromeric LRRC8A/C channel. Rutz S, Deneka D et al. Nat Struct Mol Biol. 2023 Jan;30(1):52-61.
Alignment of major-groove hydrogen bond arrays uncovers shared information between different DNA sequences that bind the same protein. Sedhom J, Kinser J, Solomon LA. NAR Genom Bioinform. 2022 Dec 31;4(4):lqac101.
Structural insights into the mechanism of the sodium/iodide symporter. Ravera S, Nicola JP et al. Nature. 2022 Dec 22;612(7941):795–801.
Structural basis for the assembly of the type V CRISPR-associated transposon complex. Schmitz M, Querques I et al. Cell. 2022 Dec 22;185(26):4999-5010.e17.
Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes. Fan C, Cohen AA et al. Immunity. 2022 Dec 13;55(12):2419-2435.e10.
A novel capsid protein network allows the characteristic internal membrane structure of Marseilleviridae giant viruses. Chihara A, Burton-Smith RN et al. Sci Rep. 2022 Dec 11;12(1):21428.
Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Gestaut D, Zhao Y et al. Cell. 2022 Dec 8;185(25):4770-4787.e20.
Molecular basis for selective activation of DREADD-based chemogenetics. Zhang S, Gumpper RH et al. Nature. 2022 Dec 8;612(7939):354–362.
Structural basis of tankyrase activation by polymerization. Pillay N, Mariotti L et al. Nature. 2022 Dec 1;612(7938):162–169.
Recognition of cyclic dinucleotides and folates by human SLC19A1. Zhang Q, Zhang X et al. Nature. 2022 Dec 1;612(7938):170–176.
Fine-mapping the immunodominant antibody epitopes on consensus sequence-based HIV-1 envelope trimer vaccine candidates. Reiss EIMM, van Haaren MM et al. NPJ Vaccines. 2022 Nov 25;7(1):152.
Three-dimensional flagella structures from animals' closest unicellular relatives, the Choanoflagellates. Pinskey JM, Lagisetty A et al. eLife. 2022 Nov 17;11:e78133.
TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand. Lim CS, Jang YH et al. Nat Commun. 2022 Nov 12;13(1):6876.
Imprinted antibody responses against SARS-CoV-2 Omicron sublineages. Park YJ, Pinto D et al. Science. 2022 Nov 11;378(6620):619-627.
Bending forces and nucleotide state jointly regulate F-actin structure. Reynolds MJ, Hachicho C et al. Nature. 2022 Nov 10;611(7935):380–386.
Bestrophin-2 and glutamine synthetase form a complex for glutamate release. Owji AP, Yu K et al. Nature. 2022 Nov 3;611(7934):180-187.
Cryo-EM structures of human m6A writer complexes. Su S, Li S et al. Cell Res. 2022 Nov;32(11):982-994.
Algorithmic design of 3D wireframe RNA polyhedra. Elonen A, Natarajan AK et al. ACS Nano. 2022 Oct 25;16(10):16608-16616.
Molecular structures reveal synergistic rescue of Δ508 CFTR by Trikafta modulators. Fiedorczuk K, Chen J. Science. 2022 Oct 21;378(6617):284-290.
Bespoke library docking for 5-HT2A receptor agonists with antidepressant activity. Kaplan AL, Confair DN et al. Nature. 2022 Oct 20;610(7932):582-591.
Structure of a mitochondrial ribosome with fragmented rRNA in complex with membrane-targeting elements. Tobiasson V, Berzina I, Amunts A. Nat Commun. 2022 Oct 17;13(1):6132.
Evolution of increased complexity and specificity at the dawn of form I Rubiscos. Schulz L, Guo Z et al. Science. 2022 Oct 14;378(6616):155-160.
Activation mechanism of the mouse cold-sensing TRPM8 channel by cooling agonist and PIP2. Yin Y, Zhang F et al. Science. 2022 Oct 14;378(6616):eadd1268.
Structures of +1 nucleosome-bound PIC-Mediator complex. Chen X, Wang X et al. Science. 2022 Oct 7;378(6615):62-68.
Structure of dynein-dynactin on microtubules shows tandem adaptor binding. Chaaban S, Carter AP. Nature. 2022 Oct 6;610(7930):212-216.
Structure-based discovery of nonopioid analgesics acting through the α2A-adrenergic receptor. Fink EA, Xu J et al. Science. 2022 Sep 30;377(6614):eabn7065.
Craspase is a CRISPR RNA-guided, RNA-activated protease. Hu C, van Beljouw SPB et al. Science. 2022 Sep 16;377(6612):1278-1285.
Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT. Ehara H, Kujirai T et al. Science. 2022 Sep 9;377(6611):eabp9466.
Structure-function analysis of the SHOC2-MRAS-PP1C holophosphatase complex. Kwon JJ, Hajian B et al. Nature. 2022 Sep 8;609(7926):408-415.
Archaic chaperone-usher pili self-secrete into superelastic zigzag springs. Pakharukova N, Malmi H et al. Nature. 2022 Sep 8;609(7926):335-340.
Structure of Tetrahymena telomerase-bound CST with polymerase α-primase. He Y, Song H et al. Nature. 2022 Aug 25;608(7924):813-818.
In situ structure and dynamics of an alphacoronavirus spike protein by cryo-ET and cryo-EM. Huang CY, Draczkowski P et al. Nat Commun. 2022 Aug 19;13(1):4877.
Cryo-EM structures of two human B cell receptor isotypes. Ma X, Zhu Y et al. Science. 2022 Aug 19;377(6608):880-885.
Intermediates in SARS-CoV-2 spike-mediated cell entry. Marcink TC, Kicmal T et al. Sci Adv. 2022 Aug 19;8(33):eabo3153.
Architecture and self-assembly of the jumbo bacteriophage nuclear shell. Laughlin TG, Deep A et al. Nature. 2022 Aug 11;608(7922):429-435.
Implementation of occupied and virtual Edmiston-Ruedenberg orbitals using Cholesky decomposed integrals. Folkestad SD, Matveeva R et al. J Chem Theory Comput. 2022 Aug 9;18(8):4733-4744.
Integrative genome modeling platform reveals essentiality of rare contact events in 3D genome organizations. Boninsegna L, Yildirim A et al. Nat Methods. 2022 Aug;19(8):938-949.
Membrane-anchored HDCR nanowires drive hydrogen-powered CO2 fixation. Dietrich HM, Righetto RD et al. Nature. 2022 Jul 28;607(7920):823-830.
Fusion protein strategies for cryo-EM study of G protein-coupled receptors. Zhang K, Wu H et al. Nat Commun. 2022 Jul 28;13(1):4366.
Characterizing and explaining the impact of disease-associated mutations in proteins without known structures or structural homologs. Sen N, Anishchenko I et al. Brief Bioinform. 2022 Jul 18;23(4):bbac187.
A peroxisomal ubiquitin ligase complex forms a retrotranslocation channel. Feng P, Wu X et al. Nature. 2022 Jul 14;607(7918):374-380.