SPOKE Index (ECM)

• Development:
  • Google docs tech meeting notes
  • Developer index: [spoke] [spokedev]
  • SPOKE github issues
  • SPOKE Google Drive
  • neighborhood UI: [spoke] [spokedev]
    • neighborhood-queries
  • first UI prototype: [spoke] [spokedev]
  • discussions:
    • Non-human-reviewed “Organism-causes-Disease” edges from PathoPhenoDB
    • possible sources of domain interaction data
    • representing pathways
• Documentation (development/in progress):
  • Nodes and Edges
  • Source Licenses
  • Edge Directionality
  • Neighborhood Explorer [spoke] [spokedev] [local, text-only]
  • Neighborhood Explorer Tutorial
• SPOKE-Related Papers
• Paper Summaries (HTML Reveal)
  • Exploring Integrative Analysis Using the BioMedical Evidence Graph (2020)
  • Network Medicine Framework for Identifying Drug Repurposing Opportunities for COVID-19 (2020)
  • Renin–Angiotensin–Aldosterone System Inhibitors in Patients with Covid-19 (2020)
  • The Network Medicine Imperative (2020)
  • The Exposome and Health (2020)
  • Extracting Medical Knowledge from EHRs (2020)
  • Pathway and Network Embedding Methods for Prioritizing Psychiatric Drugs (2020)
  • Pathogenic Gene Prediction by Multipath Random Walking on Heterogeneous Network (2019)
  • Benchmarking Molecular Networks for Disease-Gene Identification (2018)
  • Drug Network Fusion (2017)
  • MAGNETIC (2016)