example queries for http://spoke.cgl.ucsf.edu/neighborhood.html
no cutoffs yet as of test dates (below) query by protein name TSHR_HUMAN depth: 2 nodes: compound, disease, gene, protein edges: ASSOCIATES_DaG, BINDS_CbP, TRANSLATEDFROM_PtG, TREATS_CtD (11/07/2018) => 130 nodes query by protein name PTH1R_HUMAN depth: 2 nodes: compound, disease, gene, protein edges: ASSOCIATES_DaG, BINDS_CbP, TRANSLATEDFROM_PtG, TREATS_CtD (11/07/2018) => 259 nodes query by protein name RYR1_HUMAN depth: 2 nodes: compound, disease, gene, protein edges: ASSOCIATES_DaG, BINDS_CbP, TRANSLATEDFROM_PtG, TREATS_CtD (11/07/2018) => 297 nodes query by protein name BRAF_HUMAN depth: 2 nodes: compound, disease, gene, protein edges: AFFECTS_CamG, ASSOCIATES_DaG, TRANSLATEDFROM_PtG (9/26/2018) => 29 nodes (including 1 unreviewed protein and suspicious CamG links) (11/07/2018) => 226 nodes query by protein name CFTR_HUMAN depth: 2 nodes: compound, disease, gene, protein edges: AFFECTS_CamG, ASSOCIATES_DaG, TRANSLATEDFROM_PtG (9/26/2018) => 10 nodes (including 1 unreviewed protein and suspicious CamG links) (11/07/2018) => 229 nodes + TREATS_CtD (9/26/2018) => 199 nodes (mostly diseases) (11/07/2018) => 229 nodes + TREATS_CtD, BINDS_CbP (9/26/2018) => 764 nodes (11/07/2018) => 816 nodes + BINDS_CbP (11/07/2018) => 622 nodes
example compounds: CHEMBL25 aspirin CC(=O)Oc1ccccc1C(=O)O CHEMBL113 caffeine CN1C(=O)N(C)c2ncn(C)c2C1=O CHEMBL521 ibuprofen CC(C)Cc1ccc(C(C)C(=O)O)cc1 CHEMBL1686 alpha-ketoglutarate (common metabolite) CHEMBL1983268 entrectinib NTRK gene fusion inhibitor CHEMBL295316 plumbagin BindingDB entry CHEMBL297453 epigallocatechin gallate (EGCG)
example diseases: DOID:9352 type 2 diabetes mellitus