ResProp ResProp icon

ResProp is a tool for assigning the 20 standard amino acids to categories. These categories appear in the Select menu (under Select... Residue... amino acid category) and can be used in command-line specifications. There are several predefined categories. ResProp allows changing category assignments and creating new, custom categories.

There are several ways to start ResProp, a tool in the Structure Analysis category.

Under Residue Category is a pulldown menu of categories, with the name of the current (most recently chosen) category shown. Checkboxes control which of the 20 standard amino acids are assigned to the current category. Changes are applied instantly, so the category of interest should be created as needed and designated as the current category before changes are made. The default category assignments, however, can be restored with the Revert to defaults button.

Category Editing:

Changes and additions are stored in .chimera/ResProp/schemaData.py in the user's home directory and will be carried through to subsequent Chimera sessions.

Help brings up this manual page in a browser window, while Close dismisses the ResProp dialog.

Amino Acid Categories

Amino acid categories appear in the Select menu and can be used in command-line specifications. Category assignments can be changed and new categories created with ResProp. The default categorizations are taken from:

Prediction of protein secondary structure and active sites using the alignment of homologous sequences. Zvelebil MJ, Barton GJ, Taylor WR, Sternberg MJ. J Mol Biol. 1987 Jun 20;195(4):957-61.

Default Amino Acid Category Assignments
hydrophobic positivenegative polarcharged smalltiny aromatic aliphatic
ALA X X X
ARG X X X
ASN X X
ASP X X X X
CYS X X
GLU X X X
GLN X
GLY X X X
HIS X X X X X
ILE X X
LEU X X
LYS X X X X
MET X
PHE X X
PRO X
SER X X X
THR X X X
TRP X X X
TYR X X X
VAL X X X

UCSF Computer Graphics Laboratory / November 2009