[Chimera-users] fusion proteins

Elaine Meng meng at cgl.ucsf.edu
Tue Jul 28 10:10:28 PDT 2009

Hi Bren,
You can create bonds, but only within a single model, so before adding  
the bond you could use the "combine" command, or in the Model Panel,  
the "copy/combine" function to combine two models.  Then the bond can  
be added with the "bond" command or the "Build Structure" tool.

However, there is nothing in this process to prevent you from creating  
something completely ridiculous (physically unreasonable).  Chimera  
will not change the relative positions of the structures when you add  
the bond, so *before* combining the models you would need to generate  
the desired position of one structure relative to the other.

There is a little more detail and some links to the documentation in  
this previous post:

I hope this helps,
Elaine C. Meng, Ph.D.
UCSF Computer Graphics Lab (Chimera team) and Babbitt Lab
Department of Pharmaceutical Chemistry
University of California, San Francisco

On Jul 27, 2009, at 6:06 PM, Brennal Pierre wrote:

> Hi, I would like to know if it possible to create fusion proteins by  
> merging two pdb files, or if it is possible in any other way, thanks  
> Bren.

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