﻿id	summary	reporter	owner	description	type	status	priority	milestone	component	version	resolution	keywords	cc	blockedby	blocking	notify_on_close	platform	project
19110	Make mutationscores associate easier to use when sequences don't match	Tom Goddard	Tom Goddard	"Willow said associating structures with DMS data where the sequences don't quite match (e.g. mouse vs human opioid receptor) is difficult in ChimeraX.  There is a command to do it

    mutationsscores structure #1 alignSequences ABCG2_HUMAN

It requires the sequence of the DMS data is specified because their may be incomplete data.  And if you have lots of structures with several chains if you specify all of them it associates with chains that are not at all similar.

To improve this would be nice to allow aligning to the sequence derived from the DMS data maybe with option ""alignSequences true"".  Also add another option minimumSequenceIdentity defaulting to say 50% that rejects an associations that don't have a good sequence alignment."	enhancement	closed	moderate		Structure Analysis		fixed		Elaine Meng				all	ChimeraX
