[Chimera-users] modelling a dimer

Elaine Meng meng at cgl.ucsf.edu
Fri Jan 23 15:47:57 PST 2015


Hi David,
Sorry, multi-chain comparative modelling cannot be done via the Chimera-Modeller interface:
<http://www.rbvi.ucsf.edu/chimera/docs/ContributedSoftware/multalignviewer/modeller.html#comparative>

You would have to use Modeller directly to access functions such as multi-chain modeling that are not available via the Chimera graphical interface..

One could model a monomer and then open two copies of the model and superimpose them onto the monomers of a template dimer (or apply a known symmetry), but that would not necessarily exclude bad interactions between the copies.
Best,
Elaine
-----
Elaine C. Meng, Ph.D.                       
UCSF Computer Graphics Lab (Chimera team) and Babbitt Lab
Department of Pharmaceutical Chemistry
University of California, San Francisco

On Jan 23, 2015, at 2:00 PM, David Norman (Staff) <d.g.norman at dundee.ac.uk> wrote:

> I am trying to model a symmetrical dimer using modeller within Chimera. I cannot work out how to present the alignment and pdb. files in oder to do this. Any hints please.
> Thanks  David




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