[Chimera-users] mutating residues
meng at cgl.ucsf.edu
Tue Apr 8 14:59:23 PDT 2014
Dear Hussain MR,
The chimera-users at cgl.ucsf.edu address (not the others) is recommended for asking questions about using Chimera.
To change an amino acid in a protein structure, you can use the Rotamers tool (in menu under Tools… Structure Editing) or the "swapaa" command. Please see the manual:
There are "swapaa" examples in the link above, and examples of using Rotamers in the "Structure Analysis and Comparison Tutorial":
You can find tutorials and search the documentation using the Help menu in Chimera.
I hope this helps,
Elaine C. Meng, Ph.D.
UCSF Computer Graphics Lab (Chimera team) and Babbitt Lab
Department of Pharmaceutical Chemistry
University of California, San Francisco
On Apr 8, 2014, at 5:07 AM, MUHAMMAD RAMZAN MANWAR <geniouschemist26 at gmail.com> wrote:
> Dear Dr. Ferrin,
> Hope this email finds you the best of your health. First of all, I did appreciate the effort that You and Your team did in the form of UCSF Chimera. Being the part of academic/government university, I have used Chimera tool for protein modeling and cited in my two articles: one published in JCB-Wiley and other in Hundawi in 2014. Current email I am sending to request for guidance about how can I substitute an amino acid (wild type to mutant residue) within protein 3D model by using Chimera. I will be thankful for your guidance, if possible.
> With regards
> Hussain MR
> PACER-HD, KAU, KSA
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