Subject: Re: [nmr_sparky] nmr titration
From: Camilsky
Date: Jan 8, 2008

Previous: 475

Hi...
Try using Analysis module of CCPN package, that quantifies chemical shit/intensity variations upon titration.

Kamil

----- Original Message ----
From: sandra K sandramike_05@...
To: aria-discuss@yahoogroups.com; nmr_sparky@yahoogroups.com
Sent: Tuesday, 8 January, 2008 9:31:36 PM
Subject: [nmr_sparky] nmr titration

I have a quick question about nmr titratikon results.
My protein-ligand titration curves after plotting the weighted average chemical shift against ratio of the ligand looked sigmoidal. This indicated the co-operativity of the system, but I dont know how to fit those titration curves.
Any ideas? please?
SM


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