Dear all,

I have a unlabelled small protein already assigned in the past at a different pH. Since it is not labeled I have TOCSY and NOESY data at the new pH and a chemical shift assignment at the old pH.

It seems that the chemical shift change of about 0.1 ppm changing the pH.

Is there some automatic way that use the old assignments and check the NOESY pathway in the new pH data or I need to do manually step by step?

Thanks,