GPCRDB has a list of structures at http://www.gpcr.org/7tm/updates?wicket:bookmarkablePage=:nl.ru.cmbi.mcsis.web.pages.proteinstructure.ProteinStructureOverviewPage --opsin/rhodopsin 1u19 1l9h 1hzx 1f88 2i35 3cap 2.90 Park, J.H., Scheerer, P., Hofmann, K.P., Choe, H.-W., Ernst, O.P. Crystal structure of the ligand-free G-protein-coupled receptor opsin Nature 454, 183 - 187 (18 Jun 2008) http://www.nature.com/nature/journal/v454/n7201/full/nature07063.html 4a4m constitutively active N2C, M257Y, D282C rhodopsin mutant Deupi X, Edwards P, Singhal A, Nickle B, Oprian D, Schertler G, Standfuss J. Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II. Proc Natl Acad Sci U S A. 2011 Dec 23;. [Epub ahead of print] --beta1 adrenergic receptor 2vt4 2.70 cyanopindolol and stabilizing mutations Warne T, Serrano-Vega MJ, Baker JG, Moukhametzianov R, Edwards PC, Henderson R, Leslie AG, Tate CG, Schertler GF. Structure of a beta(1)-adrenergic G-protein-coupled receptor. Nature. 2008 454:486. http://www.nature.com/nature/journal/vaop/ncurrent/full/nature07101.html 2ycw 2ycx 2ycy 2ycz Moukhametzianov R, Warne T, Edwards PC, Serrano-Vega MJ, Leslie AG, Tate CG, Schertler GF. Two distinct conformations of helix 6 observed in antagonist-bound structures of a beta1-adrenergic receptor. Proc Natl Acad Sci U S A. 2011 May 17;108(20):8228-32. http://www.pnas.org/content/108/20/8228.long --beta2 adrenergic receptor 2rh1 2.40 lysozyme fusion Cherezov V, Rosenbaum DM, Hanson MA, Rasmussen SG, Thian FS, Kobilka TS, Choi HJ, Kuhn P, Weis WI, Kobilka BK, Stevens RC. High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science. 2007 Nov 23;318(5854):1258-65. http://www.sciencemag.org/cgi/content/full/318/5854/1258 3d4s 2.80 lysozyme fusion, cholesterol 2r4r 3.40 Fab complex 2r4s 3.40 Fab complex 3ny8 3ny9 3nya 3pds 3.50 lysozyme fusion, cholesterol Structure and function of an irreversible agonist-β(2) adrenoceptor complex. Rosenbaum DM, Zhang C, Lyons JA, Holl R, Aragao D, Arlow DH, Rasmussen SG, Choi HJ, Devree BT, Sunahara RK, Chae PS, Gellman SH, Dror RO, Shaw DE, Weis WI, Caffrey M, Gmeiner P, Kobilka BK. Nature. 2011 Jan 13;469(7329):236-40. 3p0g 3.50 lysozyme fusion Structure of a nanobody-stabilized active state of the β(2) adrenoceptor. Rasmussen SG, Choi HJ, Fung JJ, Pardon E, Casarosa P, Chae PS, Devree BT, Rosenbaum DM, Thian FS, Kobilka TS, Schnapp A, Konetzki I, Sunahara RK, Gellman SH, Pautsch A, Steyaert J, Weis WI, Kobilka BK. Nature. 2011 Jan 13;469(7329):175-80 3sn6 Crystal structure of the β2 adrenergic receptor-Gs protein complex. Rasmussen SG, DeVree BT, Zou Y, Kruse AC, Chung KY, Kobilka TS, Thian FS, Chae PS, Pardon E, Calinski D, Mathiesen JM, Shah ST, Lyons JA, Caffrey M, Gellman SH, Steyaert J, Skiniotis G, Weis WI, Sunahara RK, Kobilka BK. Nature. 2011 Jul 19;477(7366):549-55. doi: 10.1038/nature10361. --adenosine receptor 3eml 2.60 lysozyme fusion Jaakola VP, Griffith MT, Hanson MA, Cherezov V, Chien EY, Lane JR, Ijzerman AP, Stevens RC. The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist. Science. 2008 Nov 21;322(5905):1211-7. http://www.sciencemag.org/cgi/content/abstract/1164772v1 3qak with conformationally selective agonist Structure of an Agonist-Bound Human A2A Adenosine Receptor. Xu F, Wu H, Katritch V, Han GW, Jacobson KA, Gao ZG, Cherezov V, Stevens RC. Science. 2011 Apr 15;332(6027):322-327. 2ydo adenosine complex 2ydv NECA complex Lebon G, Warne T, Edwards PC, Bennett K, Langmead CJ, Leslie AG, Tate CG. Agonist-bound adenosine A(2A) receptor structures reveal common features of GPCR activation. Nature. 2011 May 18;474(7352):521-5. doi: 10.1038/nature10136. --dopamine D3 receptor 3pbl lysozyme fusion Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist. Chien EY, Liu W, Zhao Q, Katritch V, Han GW, Hanson MA, Shi L, Newman AH, Javitch JA, Cherezov V, Stevens RC. Science. 2010 Nov 19;330(6007):1091-5. --mu opioid receptor 4dkl 2.80 lysozyme fusion Manglik A, Kruse AC, Kobilka TS, Thian FS, Mathiesen JM, Sunahara RK, Pardo L, Weis WI, Kobilka BK, Granier S. Crystal structure of the µ-opioid receptor bound to a morphinan antagonist. Nature. 2012 Mar 21;. [Epub ahead of print] --kappa opioid receptor 4djh 2.90 lysozyme fusion --CXCR4 chemokine receptor 3odu 3oe0 3oe6 3oe8 3oe9 Structures of the CXCR4 chemokine GPCR with small-molecule and cyclic peptide antagonists. Wu B, Chien EY, Mol CD, Fenalti G, Liu W, Katritch V, Abagyan R, Brooun A, Wells P, Bi FC, Hamel DJ, Kuhn P, Handel TM, Cherezov V, Stevens RC. Science. 2010 Nov 19;330(6007):1066-71. --sphingosine 1-phosphate receptor 3v2w antagonist complex, lysozyme fusion 3v2y antagonist complex, lysozyme fusion Crystal Structure of a Lipid G Protein–Coupled Receptor. Hanson MA, Roth CB, et al. Science 17 February 2012: 851-855.