A model of Sindbis virus (PDB 1ld4) is shown using the Chimera multiscale model extension. The icosahedral virus has an outer glycoprotein shell and an inner nucleocapsid shell separated by a lipid bilayer. The glycoproteins have a coiled coil domain extending through the lipid bilayer. The model was built by fitting crystal structures of Sindbis and homolog protein components into an 11 angstrom density map obtained by cryo-electron microscopy. For more details see Wei Zhang, et al., J. Virol., (76) 11645 2002.
© 2004 The Regents of the University of California; all rights reserved.